m-PEG4-phosphonic acid
Based on 1 Customer Validation
m-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.36%
- CAS No.: 1872433-62-9
- Formula: C9H21O7P
- Molecular Weight:272.23
-
Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
|
PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1872433-62-9
-
Appearance Oil
-
Molecular Weight 272.23
-
Formula C9H21O7P
-
Color Brown to reddish brown
-
SMILES
COCCOCCOCCOCCP(O)(O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (91.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (266 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6734 mL | 18.3668 mL | 36.7336 mL | 91.8341 mL |
| 5 mM | 0.7347 mL | 3.6734 mL | 7.3467 mL | 18.3668 mL | |
| 10 mM | 0.3673 mL | 1.8367 mL | 3.6734 mL | 9.1834 mL | |
| 15 mM | 0.2449 mL | 1.2245 mL | 2.4489 mL | 6.1223 mL | |
| 20 mM | 0.1837 mL | 0.9183 mL | 1.8367 mL | 4.5917 mL | |
| 25 mM | 0.1469 mL | 0.7347 mL | 1.4693 mL | 3.6734 mL | |
| 30 mM | 0.1224 mL | 0.6122 mL | 1.2245 mL | 3.0611 mL | |
| 40 mM | 0.0918 mL | 0.4592 mL | 0.9183 mL | 2.2959 mL | |
| 50 mM | 0.0735 mL | 0.3673 mL | 0.7347 mL | 1.8367 mL | |
| 60 mM | 0.0612 mL | 0.3061 mL | 0.6122 mL | 1.5306 mL | |
| 80 mM | 0.0459 mL | 0.2296 mL | 0.4592 mL | 1.1479 mL |
Powered by Bioz