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  3. Biotin-PEG4-Dde-TAMRA-PEG3-Azide

Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

Biotin-PEG4-Dde-TAMRA-PEG3-Azide Chemical Structure

Biotin-PEG4-Dde-TAMRA-PEG3-Azide Chemical Structure

CAS No. : 2353409-56-8

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Description

Biotin-PEG4-Dde-TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) modified with a cleavable biotin group. Biotin-PEG4-Dde-TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

IC50 & Target

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1397.64

Formula

C69H96N12O17S

CAS No.
SMILES

[O-]C(C(C=C(C(NCCC(N(CCOCCOCCOCCN=[N+]=[N-])CCC(NCCCN/C(CCOCCOCCOCCOCCNC(CCCC[C@H]1[C@](NC2=O)([H])[C@](N2)([H])CS1)=O)=C(C3=O)\C(CC(C)(C)C3)=O)=O)=O)=O)C=C4)=C4C5=C(C=CC(N)=C6)C6=[O+]C7=C5C=CC(N(C)C)=C7)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Biotin-PEG4-Dde-TAMRA-PEG3-Azide Related Classifications

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Product Name:
Biotin-PEG4-Dde-TAMRA-PEG3-Azide
Cat. No.:
HY-141091
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