1. PROTAC
  2. PROTAC Linkers
  3. Ms-PEG4-Ms

Ms-PEG4-Ms  (Synonyms: 1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane)

Cat. No.: HY-42774 Purity: ≥95.0%
COA Handling Instructions

Ms-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Ms-PEG4-Ms Chemical Structure

Ms-PEG4-Ms Chemical Structure

CAS No. : 55400-73-2

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500 mg USD 80 In-stock
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This product is a controlled substance and not for sale in your territory.

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Description

Ms-PEG4-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

350.41

Formula

C10H22O9S2

CAS No.
Appearance

Liquid

Color

Light yellow to yellow

SMILES

CS(OCCOCCOCCOCCOS(C)(=O)=O)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Ms-PEG4-Ms Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ms-PEG4-Ms
Cat. No.:
HY-42774
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