Mc-PEG4-Val-Ala-PAB-Exatecan
Based on 1 Customer Validation
Mc-PEG4-Val-Ala-PAB-Exatecan is a Drug-linker conjugate for ADC. Mc-PEG4-Val-Ala-PAB-Exatecan contains the ADC linker (Mc-PEG4-Val-Ala-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631).
For research use only. We do not sell to patients.
- Purity: 99.65%
- Formula: C58H69FN8O16
- Molecular Weight:1153.21
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1153.21
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Formula C58H69FN8O16
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Color White to yellow
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SMILES
O=C(OCC(C=C1)=CC=C1NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (86.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.8671 mL | 4.3357 mL | 8.6714 mL | 21.6786 mL |
| 5 mM | 0.1734 mL | 0.8671 mL | 1.7343 mL | 4.3357 mL | |
| 10 mM | 0.0867 mL | 0.4336 mL | 0.8671 mL | 2.1679 mL | |
| 15 mM | 0.0578 mL | 0.2890 mL | 0.5781 mL | 1.4452 mL | |
| 20 mM | 0.0434 mL | 0.2168 mL | 0.4336 mL | 1.0839 mL | |
| 25 mM | 0.0347 mL | 0.1734 mL | 0.3469 mL | 0.8671 mL | |
| 30 mM | 0.0289 mL | 0.1445 mL | 0.2890 mL | 0.7226 mL | |
| 40 mM | 0.0217 mL | 0.1084 mL | 0.2168 mL | 0.5420 mL | |
| 50 mM | 0.0173 mL | 0.0867 mL | 0.1734 mL | 0.4336 mL | |
| 60 mM | 0.0145 mL | 0.0723 mL | 0.1445 mL | 0.3613 mL | |
| 80 mM | 0.0108 mL | 0.0542 mL | 0.1084 mL | 0.2710 mL |
Mc-PEG4-Val-Ala-PAB-Exatecan Related Classifications
HY-171580 Related Classifications
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