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Cat. No.: HY-130312

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N-(Azido-PEG4)-N-Boc-PEG4-NHS ester

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

CAS No.: 2112731-96-9
Formula: C₂₈H₄₉N₅O₁₃
Molecular Weight:663.71

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester Chemical Structure

CAS No.: 2112731-96-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs^[1] N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC₅₀ & Target

PEGs

All PROTAC Linkers Isoforms :

Chemical Information

CAS No. 2112731-96-9
Appearance Liquid
Molecular Weight 663.71
Formula C₂₈H₄₉N₅O₁₃
Color Colorless to off-white
SMILES

O=C(OC(C)(C)C)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester

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Biological Activity
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N-(Azido-PEG4)-N-Boc-PEG4-NHS ester

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester

N-(Azido-PEG2)-N-Boc-PEG4-NHS ester

N-(Azido-PEG2)-N-Boc-PEG3-Boc

N-(Azido-PEG2)-N-Boc-PEG4-acid

N-(Azido-PEG3)-N-Boc-PEG4-Boc

N-Azido-PEG4-N-Boc-N-PEG3-Boc

N-Boc-N-bis(PEG3-azide)

N-(Azido-PEG2)-N-Boc-PEG3-acid

N-Boc-N-bis(PEG4-azide)

N-(Azido-PEG3)-N-Boc-PEG4-acid

N-(Azido-PEG3)-N-Boc-PEG3-acid

N-(Azido-PEG3)-N-Boc-PEG3-NHS ester

All PROTAC Linkers Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bioz

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester

N-(Azido-PEG2)-N-Boc-PEG3-NHS ester

N-(Azido-PEG2)-N-Boc-PEG4-NHS ester

N-(Azido-PEG2)-N-Boc-PEG3-Boc

N-(Azido-PEG2)-N-Boc-PEG4-acid

N-(Azido-PEG3)-N-Boc-PEG4-Boc

N-Azido-PEG4-N-Boc-N-PEG3-Boc

N-Boc-N-bis(PEG3-azide)

N-(Azido-PEG2)-N-Boc-PEG3-acid

N-Boc-N-bis(PEG4-azide)

N-(Azido-PEG3)-N-Boc-PEG4-acid

N-(Azido-PEG3)-N-Boc-PEG3-acid

N-(Azido-PEG3)-N-Boc-PEG3-NHS ester

All PROTAC Linkers Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester Related Classifications

HY-130312 Related Classifications

Bioz