2112731-96-9
Chemical Structure
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester
- CAS No.: 2112731-96-9
- Formula:C28H49N5O13
- Molecular Weight:663.71
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 1-azido-12-(tert-butoxycarbonyl)-3,6,9,15,18,21,24-heptaoxa-12-azaheptacosan-27-oate
InChIKey: HPZJDOZGYDPWNJ-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)N(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
Biological Activity: N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs[1] N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(Azido-PEG4)-N-Boc-PEG4-NHS ester | N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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