tri(GalNAc-PEG2)-PEG4-cyclo(Ac-DCAW-{Arg(3F-Ph)-PEG2}-LGELVWCT) (Cys2-Cys12)
Based on 1 Customer Validation
tri(GalNAc-PEG2)-PEG4-cyclo(Ac-DCAW-{Arg(3F-Ph)-PEG2}-LGELVWCT) (Cys2-Cys12) is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research.
For research use only. We do not sell to patients.
- Purity : 99.46%
- CAS No.: 3099288-71-5
- Formula: C152H236FN25O62S2
- Molecular Weight:3488.76
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Description
Chemical Information
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CAS No. 3099288-71-5
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Appearance Solid
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Molecular Weight 3488.76
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Formula C152H236FN25O62S2
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Color White to off-white
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SMILES
O=C1N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)CSSC[C@H](NC([C@H](CC(O)=O)NC(C)=O)=O)C(N[C@@H](C)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC(NCC4=CC(F)=C(OC(CCOCCOCCNC(CCOCCOCCOCCOCCC(NCC(NC(COCCC(NCCOCCOCCO[C@H]5[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O5)=O)(COCCC(NCCOCCOCCO[C@H]6[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O6)=O)COCCC(NCCOCCOCCO[C@H]7[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O7)=O)=O)=O)=O)=O)C=C4)=O)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@H]1CC8=CNC9=CC=CC=C89)=O)=O)=O)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 33.33 mg/mL (9.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.2866 mL | 1.4332 mL | 2.8663 mL | 7.1659 mL |
| 5 mM | 0.0573 mL | 0.2866 mL | 0.5733 mL | 1.4332 mL |