TAMRA-PEG4-acid
TAMRA-PEG4-acid is a dye derivative of TAMRA (HY-135640) containing 3 PEG units.
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- No. CAS: 1909223-02-4
- Fòrmula: C36H43N3O10
- Peso molecular:677.80
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Almacenamiento:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1909223-02-4
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Appearance Liquid
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Peso molecular 677.80
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Fòrmula C36H43N3O10
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Color Brown to reddish brown
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SMILES
C/[N+](C)=C1C=CC2=C(C3=CC=C(C(NCCOCCOCCOCCOCCC(O)=O)=O)C=C3C([O-])=O)C4=CC=C(N(C)C)C=C4OC2=C/1.C/[N+](C)=C5C=CC6=C(C7=CC(C(NCCOCCOCCOCCOCCC(O)=O)=O)=CC=C7C([O-])=O)C8=CC=C(N(C)C)C=C8OC6=C/5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 100 mg/mL (147.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4754 mL | 7.3768 mL | 14.7536 mL | 36.8840 mL |
| 5 mM | 0.2951 mL | 1.4754 mL | 2.9507 mL | 7.3768 mL | |
| 10 mM | 0.1475 mL | 0.7377 mL | 1.4754 mL | 3.6884 mL | |
| 15 mM | 0.0984 mL | 0.4918 mL | 0.9836 mL | 2.4589 mL | |
| 20 mM | 0.0738 mL | 0.3688 mL | 0.7377 mL | 1.8442 mL | |
| 25 mM | 0.0590 mL | 0.2951 mL | 0.5901 mL | 1.4754 mL | |
| 30 mM | 0.0492 mL | 0.2459 mL | 0.4918 mL | 1.2295 mL | |
| 40 mM | 0.0369 mL | 0.1844 mL | 0.3688 mL | 0.9221 mL | |
| 50 mM | 0.0295 mL | 0.1475 mL | 0.2951 mL | 0.7377 mL | |
| 60 mM | 0.0246 mL | 0.1229 mL | 0.2459 mL | 0.6147 mL | |
| 80 mM | 0.0184 mL | 0.0922 mL | 0.1844 mL | 0.4611 mL | |
| 100 mM | 0.0148 mL | 0.0738 mL | 0.1475 mL | 0.3688 mL |