Sulfo DBCO-PEG4-amine
Based on 1 Customer Validation
Sulfo DBCO-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.65%
- CAS No.: 2055198-05-3
- Formula: C32H42N4O10S
- Molecular Weight:674.76
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2055198-05-3
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Appearance Solid
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Molecular Weight 674.76
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Formula C32H42N4O10S
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Color Off-white to yellow
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SMILES
O=C(CCOCCOCCOCCOCCN)NCC(S(=O)(O)=O)C(NCCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (148.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4820 mL | 7.4100 mL | 14.8201 mL | 37.0502 mL |
| 5 mM | 0.2964 mL | 1.4820 mL | 2.9640 mL | 7.4100 mL | |
| 10 mM | 0.1482 mL | 0.7410 mL | 1.4820 mL | 3.7050 mL | |
| 15 mM | 0.0988 mL | 0.4940 mL | 0.9880 mL | 2.4700 mL | |
| 20 mM | 0.0741 mL | 0.3705 mL | 0.7410 mL | 1.8525 mL | |
| 25 mM | 0.0593 mL | 0.2964 mL | 0.5928 mL | 1.4820 mL | |
| 30 mM | 0.0494 mL | 0.2470 mL | 0.4940 mL | 1.2350 mL | |
| 40 mM | 0.0371 mL | 0.1853 mL | 0.3705 mL | 0.9263 mL | |
| 50 mM | 0.0296 mL | 0.1482 mL | 0.2964 mL | 0.7410 mL | |
| 60 mM | 0.0247 mL | 0.1235 mL | 0.2470 mL | 0.6175 mL | |
| 80 mM | 0.0185 mL | 0.0926 mL | 0.1853 mL | 0.4631 mL | |
| 100 mM | 0.0148 mL | 0.0741 mL | 0.1482 mL | 0.3705 mL |
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