PC-Biotin-PEG4-NHS carbonate
Based on 1 Customer Validation
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 2055198-03-1
- Formula: C35H50N6O14S
- Molecular Weight:810.87
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
|
PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2055198-03-1
-
Appearance Solid
-
Molecular Weight 810.87
-
Formula C35H50N6O14S
-
Color White to off-white
-
SMILES
O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(NCCOCCOCCOCCOCCC(NCC3=CC(C(OC(ON4C(CCC4=O)=O)=O)C)=C([N+]([O-])=O)C=C3)=O)=O)[H]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (61.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2332 mL | 6.1662 mL | 12.3324 mL | 30.8311 mL |
| 5 mM | 0.2466 mL | 1.2332 mL | 2.4665 mL | 6.1662 mL | |
| 10 mM | 0.1233 mL | 0.6166 mL | 1.2332 mL | 3.0831 mL | |
| 15 mM | 0.0822 mL | 0.4111 mL | 0.8222 mL | 2.0554 mL | |
| 20 mM | 0.0617 mL | 0.3083 mL | 0.6166 mL | 1.5416 mL | |
| 25 mM | 0.0493 mL | 0.2466 mL | 0.4933 mL | 1.2332 mL | |
| 30 mM | 0.0411 mL | 0.2055 mL | 0.4111 mL | 1.0277 mL | |
| 40 mM | 0.0308 mL | 0.1542 mL | 0.3083 mL | 0.7708 mL | |
| 50 mM | 0.0247 mL | 0.1233 mL | 0.2466 mL | 0.6166 mL | |
| 60 mM | 0.0206 mL | 0.1028 mL | 0.2055 mL | 0.5139 mL |
PC-Biotin-PEG4-NHS carbonate Related Classifications
HY-140135 Related Classifications
Powered by Bioz