N-Desthiobiotin-N-bis(PEG4-NHS ester)
N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 2353409-61-5
- Formula: C40H65N5O18
- Molecular Weight:903.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTAC Linkers Isoforms
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Biological Activity
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2353409-61-5
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Molecular Weight 903.97
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Formula C40H65N5O18
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SMILES
O=C(CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(ON(C1=O)C(CC1)=O)=O)C(CCCCC[C@@H](NC2=O)[C@@H](N2)C)=O)ON(C3=O)C(CC3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)