Mal-PEG4-C2-NH2 TFA
Based on 1 Customer Validation
Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.60%
- CAS No.: 2512227-13-1
- Formula: C16H25F3N2O8
- Molecular Weight:430.37
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2512227-13-1
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Appearance Liquid
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Molecular Weight 430.37
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Formula C16H25F3N2O8
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Color Light yellow to yellow
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SMILES
NCCOCCOCCOCCOCCN1C(C=CC1=O)=O.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 175 mg/mL (406.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3236 mL | 11.6179 mL | 23.2358 mL | 58.0896 mL |
| 5 mM | 0.4647 mL | 2.3236 mL | 4.6472 mL | 11.6179 mL | |
| 10 mM | 0.2324 mL | 1.1618 mL | 2.3236 mL | 5.8090 mL | |
| 15 mM | 0.1549 mL | 0.7745 mL | 1.5491 mL | 3.8726 mL | |
| 20 mM | 0.1162 mL | 0.5809 mL | 1.1618 mL | 2.9045 mL | |
| 25 mM | 0.0929 mL | 0.4647 mL | 0.9294 mL | 2.3236 mL | |
| 30 mM | 0.0775 mL | 0.3873 mL | 0.7745 mL | 1.9363 mL | |
| 40 mM | 0.0581 mL | 0.2904 mL | 0.5809 mL | 1.4522 mL | |
| 50 mM | 0.0465 mL | 0.2324 mL | 0.4647 mL | 1.1618 mL | |
| 60 mM | 0.0387 mL | 0.1936 mL | 0.3873 mL | 0.9682 mL | |
| 80 mM | 0.0290 mL | 0.1452 mL | 0.2904 mL | 0.7261 mL | |
| 100 mM | 0.0232 mL | 0.1162 mL | 0.2324 mL | 0.5809 mL |
Mal-PEG4-C2-NH2 TFA Related Classifications
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