Cl-C6-PEG4-O-CH2COOH
Based on 1 Customer Validation
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1799506-30-1
- Formula: C16H31ClO7
- Molecular Weight:370.87
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1799506-30-1
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Appearance Oil
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Molecular Weight 370.87
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Formula C16H31ClO7
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Color Colorless to light yellow
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SMILES
ClCCCCCCOCCOCCOCCOCCOCC(O)=O
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Synonyms
PROTAC Linker 4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Ethanol : 100 mg/mL (269.64 mM; Need ultrasonic)
DMSO : 100 mg/mL (269.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 2.6964 mL | 13.4818 mL | 26.9636 mL | 67.4091 mL |
| 5 mM | 0.5393 mL | 2.6964 mL | 5.3927 mL | 13.4818 mL | |
| 10 mM | 0.2696 mL | 1.3482 mL | 2.6964 mL | 6.7409 mL | |
| 15 mM | 0.1798 mL | 0.8988 mL | 1.7976 mL | 4.4939 mL | |
| 20 mM | 0.1348 mL | 0.6741 mL | 1.3482 mL | 3.3705 mL | |
| 25 mM | 0.1079 mL | 0.5393 mL | 1.0785 mL | 2.6964 mL | |
| 30 mM | 0.0899 mL | 0.4494 mL | 0.8988 mL | 2.2470 mL | |
| 40 mM | 0.0674 mL | 0.3370 mL | 0.6741 mL | 1.6852 mL | |
| 50 mM | 0.0539 mL | 0.2696 mL | 0.5393 mL | 1.3482 mL | |
| 60 mM | 0.0449 mL | 0.2247 mL | 0.4494 mL | 1.1235 mL | |
| 80 mM | 0.0337 mL | 0.1685 mL | 0.3370 mL | 0.8426 mL | |
| 100 mM | 0.0270 mL | 0.1348 mL | 0.2696 mL | 0.6741 mL |
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