Gly-Gly-Gly-PEG4-DBCO
Based on 1 Customer Validation
Gly-Gly-Gly-PEG4-DBCO is a 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Gly-Gly-Gly-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 95.19%
- CAS No.: 2353409-80-8
- Formula: C35H46N6O9
- Molecular Weight:694.77
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2353409-80-8
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Appearance Solid
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Molecular Weight 694.77
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Formula C35H46N6O9
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Color Light yellow to yellow
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SMILES
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCCNC(CNC(CNC(CN)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (143.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4393 mL | 7.1966 mL | 14.3933 mL | 35.9831 mL |
| 5 mM | 0.2879 mL | 1.4393 mL | 2.8787 mL | 7.1966 mL | |
| 10 mM | 0.1439 mL | 0.7197 mL | 1.4393 mL | 3.5983 mL | |
| 15 mM | 0.0960 mL | 0.4798 mL | 0.9596 mL | 2.3989 mL | |
| 20 mM | 0.0720 mL | 0.3598 mL | 0.7197 mL | 1.7992 mL | |
| 25 mM | 0.0576 mL | 0.2879 mL | 0.5757 mL | 1.4393 mL | |
| 30 mM | 0.0480 mL | 0.2399 mL | 0.4798 mL | 1.1994 mL | |
| 40 mM | 0.0360 mL | 0.1799 mL | 0.3598 mL | 0.8996 mL | |
| 50 mM | 0.0288 mL | 0.1439 mL | 0.2879 mL | 0.7197 mL | |
| 60 mM | 0.0240 mL | 0.1199 mL | 0.2399 mL | 0.5997 mL | |
| 80 mM | 0.0180 mL | 0.0900 mL | 0.1799 mL | 0.4498 mL | |
| 100 mM | 0.0144 mL | 0.0720 mL | 0.1439 mL | 0.3598 mL |
Gly-Gly-Gly-PEG4-DBCO Related Classifications
HY-140309 Related Classifications
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