2. PROTAC Linker
  3. Biotin-PEG4-NHS ester

Biotin-PEG4-NHS ester 

Cat. No.: HY-140889 Purity: 98.08%
Handling Instructions

Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Biotin-PEG4-NHS ester Chemical Structure

Biotin-PEG4-NHS ester Chemical Structure

CAS No. : 459426-22-3

Size Price Stock Quantity
50 mg USD 140 In-stock
Estimated Time of Arrival: December 31
100 mg USD 240 In-stock
Estimated Time of Arrival: December 31
250 mg USD 480 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

View All PROTAC Linker Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target



In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight







O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCNC(CCCC[[email protected]@H]2SC[[email protected]]([[email protected]]2([H])N3)([H])NC3=O)=O


Room temperature in continental US; may vary elsewhere.


-20°C, protect from light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (424.69 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6987 mL 8.4937 mL 16.9874 mL
5 mM 0.3397 mL 1.6987 mL 3.3975 mL
10 mM 0.1699 mL 0.8494 mL 1.6987 mL
*Please refer to the solubility information to select the appropriate solvent.
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2


Biotin-PEG4-NHS esterPROTAC LinkerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name



Applicant Name *


Email address *

Phone number *


Organization name *

Department *


Requested quantity *

Country or Region *



Bulk Inquiry

Inquiry Information

Product Name:
Biotin-PEG4-NHS ester
Cat. No.:
MCE Japan Authorized Agent: