1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Gly-Gly-Gly-PEG2-azide

Gly-Gly-Gly-PEG2-azide is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Gly-Gly-Gly-PEG2-azide Chemical Structure

Gly-Gly-Gly-PEG2-azide Chemical Structure

CAS No. : 2222277-20-3

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5 mg USD 150 In-stock
10 mg USD 240 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Gly-Gly-Gly-PEG2-azide is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

Molecular Weight

345.35

Formula

C12H23N7O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCCOCCOCCNC(CNC(CNC(CN)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (144.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8956 mL 14.4781 mL 28.9561 mL
5 mM 0.5791 mL 2.8956 mL 5.7912 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8956 mL 14.4781 mL 28.9561 mL 72.3903 mL
5 mM 0.5791 mL 2.8956 mL 5.7912 mL 14.4781 mL
10 mM 0.2896 mL 1.4478 mL 2.8956 mL 7.2390 mL
15 mM 0.1930 mL 0.9652 mL 1.9304 mL 4.8260 mL
20 mM 0.1448 mL 0.7239 mL 1.4478 mL 3.6195 mL
25 mM 0.1158 mL 0.5791 mL 1.1582 mL 2.8956 mL
30 mM 0.0965 mL 0.4826 mL 0.9652 mL 2.4130 mL
40 mM 0.0724 mL 0.3620 mL 0.7239 mL 1.8098 mL
50 mM 0.0579 mL 0.2896 mL 0.5791 mL 1.4478 mL
60 mM 0.0483 mL 0.2413 mL 0.4826 mL 1.2065 mL
80 mM 0.0362 mL 0.1810 mL 0.3620 mL 0.9049 mL
100 mM 0.0290 mL 0.1448 mL 0.2896 mL 0.7239 mL
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Gly-Gly-Gly-PEG2-azide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Gly-Gly-Gly-PEG2-azide
Cat. No.:
HY-157275
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