ARX305 Antibody
ARX305 Antibody is a high-affinity, humanized anti-CD70 antibody. ARX305 Antibody forms an antibody-drug conjugate (ADC) (ARX305) with the potent microtubule inhibitor PEG4-aminooxy-MMAF (AS269) (HY-128968). As a targeting component, ARX305 Antibody mediates the binding and internalization of ARX305 to CD70-positive tumor cells, whereas the unconjugated ARX305 Antibody exhibits only weak anti-tumor activity in various xenograft and disseminated tumor models. ARX305 Antibody can be used in the research of a variety of solid tumors and hematological malignancies.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Human IgG1 kappa (without para-acetyl phenylalanine (pAF))
Human
TNFSF7/CD27L/CD70
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
化学情報
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
ARX305 Antibody 関連分類
HY-P991930 関連分類
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