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Results for "

biotin-

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (258) Cardiovascular Disease (8) Endocrinology (7) Infection (25) Inflammation/Immunology (34) Metabolic Disease (49) Neurological Disease (22)
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170

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Isotope-Labeled Compounds

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102

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0511

*Biotin* Maximum Cited Publications 26 Publications Verification Vitamin B7; Vitamin H; D-biotin	Environmental Pollutants Endogenous Metabolite	Metabolic Disease
Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-D0802

Biotin NHS Maximum Cited Publications 19 Publications Verification biotin N-hydroxysuccinimide ester; NHS-biotin	Fluorescent Dye	Others
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.

HY-136769

Biotin-HPDP 2 Publications Verification	Biochemical Assay Reagents	Others
Biotin-HPDP is a biochemical reagent. Biotin-HPDP can couple with GMPS and label free protein thiols. Biotin-HPDP can be used as a biological material or organic compound for life science related research .

HY-141898

Biotin-4-aminophenol	Fluorescent Dye	Others
Biotin-4-aminophenol is a biotin-phenol analog. Biotin-4-aminophenol generates free radicals and conjugates to tyrosine residues in proteins more efficiently and selectively than the previously reported BP1 .

HY-139912

Biotin-aniline	DNA Stain Biochemical Assay Reagents	Others
Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline is also a novel APEX2 substrate. Biotin-aniline can label proteins via miniSOG. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity .

HY-W808757

Biotin-maleimide	Biochemical Assay Reagents	Others
Biotin-maleimide is a biotinylated biochemical detection reagent that acts as a thiol-specific probe. Biotin-maleimide can also be used to prepare biotin-conjugated polychelators .

HY-P11307

Biotin-epoxomicin	Proteasome	Cancer
Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma .

HY-156197

Biotin-cholesterol	Liposome Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Cancer
Biotin-cholesterol is a biotinylated form of Cholesterol (HY-N0322). Biotin-cholesterol can be used in the synthesis of biotin-conjugated liposomes and micelles for drug delivery .

HY-159057

Biotin-BMCC	Biochemical Assay Reagents	Others
Biotin-BMCC is a Maliemide (HY-W007324) conjugated biotin molecule that has a high affinity for free thiol groups of cysteines .

HY-P11306

Biotin-(Oaa)3-epoxomicin	Proteasome NF-κB	Inflammation/Immunology
Biotin-(Oaa)₃-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)₃-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain .

HY-D0980

Biotin-DADOO biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-biotin	Biochemical Assay Reagents	Infection
Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-113268

Biotin sulfone 2 Publications Verification	Endogenous Metabolite	Metabolic Disease
Biotin sulfone, a structural analog and metabolite of Biotin (HY-B0511), exerts competitive inhibition against Biotin in Lactobacillus arabinosus 17-5 .

HY-D1635

Sulfo-NHS-LC-LC-Biotin biotin-XX-SSE	Fluorescent Dye Exosomes	Infection
Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .

HY-D1668

Biotin-11-dCTP	DNA Stain Reverse Transcriptase	Infection Neurological Disease Cancer
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

HY-145152

Biotin-Thalidomide	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Biotin-Thalidomide is a biotin-conjugated Thalidomide (HY-14658) for binding to CRBN. Biotin-Thalidomide can be used to synthesize PROTAC .

HY-D1669

Biotin-11-UTP	Fluorescent Dye	Others
Biotin-11-UTP is a Biotin-labeled uridine triphosphate (UTP), containing 11 atoms in the linker between biotin and UTP. Biotin-11-UTP can biotinylate transcribed RNA in vitro and has been widely used as labeling RNA probe . Biotin-11-UTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0389F

Biotin-D-Glucose	Drug Derivative	Others
Biotin-D-Glucose is a biotin-conjugated glucose derivative .

HY-P3576A

Biotin-Gastrin Releasing Peptide, human TFA	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-141793

ATRA-biotin biotin-ATRA-conjugate	RAR/RXR PPAR Endogenous Metabolite Autophagy	Cancer
ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue .

HY-140656A

**Biotin-PEG-Biotin**	PROTAC Linkers	Cancer
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-D1686

Biotin-16-UTP biotin-16-UTP tetralithium	DNA Stain	Others
Biotin-16-UTP is an active substrate for RNA polymerase. Biotin-16-UTP can replace UTP in the in vitro transcription reaction for RNA labeling .

HY-W156324

Biotin-PEGn-NHS ester	PROTAC Linkers Liposome	Others
Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA) .

HY-B0511R

Biotin (Standard) Vitamin B7 (Standard); Vitamin H (Standard); D-biotin (Standard)	Endogenous Metabolite Reference Standards	Metabolic Disease
Biotin (Standard) is the analytical standard of Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-P2136F

Biotin-COG1410 TFA	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .

HY-13948F

Biotin-Ahx-Angiotensin II human biotin-Ahx-Angiotensin II; biotin-Ahx-Ang II; biotin-Ahx-DRVYIHPF	Angiotensin Receptor	Others
Biotin-Ahx-Angiotensin II human (Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF) is a biological active peptide. (biotin labeled HY-13948)

HY-D1022A

Biotin-16-dUTP trisodium biotin-16-deoxyuridine-5'-triphosphate trisodium	DNA Stain	Others
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-P11118A

Biotinylated CCDC61 peptide TFA CAPture peptide, biotin-CCDC61 (334-366) TFA	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .

HY-17571F

Biotin-Oxytocin biotin-α-Hypophamine; biotin-Oxytocic hormone	Oxytocin Receptor	Others
Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biological active peptide. (This is Oxytocin (HY-17571) N-terminally labeled with Biotin.)

HY-140656H

**Biotin-PEG40000-Biotin**	Biochemical Assay Reagents	Others
Biotin-PEG40000-Biotin can be used for crosslinking PEGylation by binding to two streptavidin and avidin. Biotin is conjugated to a linear PEG through a stable amide linker .

HY-158099

Biotin-Cel Celastrol-biotin	Biochemical Assay Reagents	Cancer
Biotin-Cel (Celastrol-Biotin) is a biotin-labeled Celastrol (HY-13067). Celastrol exhibits antitumor, anti-inflammatory, and anti-obesity activities. Biotin-Cel can be used in biotin-affinity pulldown assay to identify the molecular target of Celastrol in hepatocellular carcinoma cells .

HY-D1022

Biotin-16-dUTP biotin-16-deoxyuridine-5'-triphosphate	Fluorescent Dye	Others
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-151714

Biotin-MeTz	ADC Linker	Others
Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates .

HY-160841

Biotin-16-dCTP	DNA Stain DNA/RNA Synthesis	Others
Biotin-16-dCTP is a biotinylated deoxycytidine triphosphate that serves as an important DNA labeling substrate. Biotin-16-dCTP can be enzymatically incorporated into the 3' end of DNA probes via terminal deoxynucleotidyl transferase, forming a 1-3 nucleotide-long tail to achieve biotinylation of the probes. Biotin-16-dCTP enhances chemiluminescent detection of low-abundance targets such as specific tRNA isoacceptors through Northern blotting. Biotin-16-dCTP can also replace conventional dCTP to be integrated into single-stranded DNA generated by asymmetric polymerase chain reaction, which is applicable for bioconjugation or pull-down assays. Repeated freeze-thaw cycles of Biotin-16-dCTP should be avoided to prevent degradation of its function for probe biotinylation .

HY-D1686B

Biotin-16-UTP tetrasodium	DNA Stain	Others
Biotin-16-UTP tetrasodium is an active substrate for RNA polymerase. Biotin-16-UTP tetrasodium can replace UTP in the in vitro transcription reaction for RNA labeling .

HY-W591393

Biotin Azide Plus	Biochemical Assay Reagents	Cancer
Biotin Azide Plus is an oxazolidine reagent that integrates azide-biotin click chemistry and a photocleavable linker arm. Biotin Azide Plus not only reacts with biotin thioether to form stable sulfinimide products, but also enables bioconjugation of proteins and DNA through biotin redox-activated chemical labeling technology. Taking advantage of the streptavidin capture and photo-release properties, Biotin Azide Plus effectively facilitates the isolation of lipid-derived electrophile-protein adducts, thus finding wide application in scientific research related to fields such as SKBR3 cancer .

HY-D1029A

Biotin-11-dUTP trisodium 1 Publications Verification	Fluorescent Dye	Others
Biotin-11-dUTP trisodium is a fluorescent substitute for dTTP.

HY-146244A

Biotin-labeled agatolimod sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
Biotin-labeled agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. Biotin-labeled agatolimod (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.

HY-P2549

Biotin-β-Amyloid (1-40)	Fluorescent Dye	Neurological Disease
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.

HY-140656F

**Biotin-PEG20000-Biotin**	Fluorescent Dye	Others
Biotin-PEG20000-Biotin is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity.

HY-125501

Biotin-XX hydrazide biotin-(AC5)2-hydrazide	Biochemical Assay Reagents	Others
Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding .

HY-152965

Biotin-doxorubicin	Topoisomerase Antibiotic Apoptosis Autophagy	Infection Cancer
Biotin-doxorubicin is a Biotin-labeled Doxorubicin. Doxorubicin, a broad-spectrum anthracycline antibiotic, is a topoisomerase II inhibitor .

HY-176206H

Biotin-PEG40000-COOH	Biochemical Assay Reagents	Others
Biotin-PEG40000-COOH is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG40000-COOH can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .

HY-174938

Biotin-PEG3-Iodoacetamide	Biochemical Assay Reagents	Others
Biotin-PEG3-Iodoacetamide is a PEG derivative composed of Biotin, 3 PEG units, and Iodoacetamide. Biotin can form a stable non-covalent bond with streptavidin.

HY-174914

Biotin-PEG4-mal	Biochemical Assay Reagents	Others
Biotin-PEG4-mal is a PEG derivative composed of Biotin, 4 PEG units and Maleimide. Biotin can form a stable non-covalent bond with streptavidin.

HY-P10569

Biotin HER-2 substrate peptide	EGFR	Cancer
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a K_m value of 60 μm for Her2/neu kinase domain .

HY-140656E

**Biotin-PEG10000-Biotin**	PROTAC Linkers	Cancer
Biotin-PEG10000-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-W1048533H

Biotin-PEG1000-SH biotin-PEG1000-Thiol	Biochemical Assay Reagents	Others
Biotin-PEG1000-SH (Biotin-PEG1000-Thiol) is a biotin PEG polymer containing a thiol (-SH). Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-116027A

Biotin-PEG10-acid biotin-PEG10-COOH	Biochemical Assay Reagents	Others
Biotin-PEG10-acid (Biotin-PEG10-COOH) is a biotin-PEG compound containing a carboxyl group (-COOH) that can be used to react with an amine group (NH2) to form a stable amide bond. Biotin-PEG10-acid can be used for protein labeling and drug delivery research .

HY-157221

Biotin-16-dGTP tetralithium	Nucleoside Antimetabolite/Analog	Others
Biotin-16-dGTP tetralithium is a Biotin labeled dGTP, and can be used to label oligonucleotides .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0511

*Biotin* Maximum Cited Publications 26 Publications Verification Vitamin B7; Vitamin H; D-biotin	Structural Classification Immune System Disorder Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-128699

D-Desthiobiotin Dethiobiotin	Alkaloids Human Gut Microbiota Metabolites Microorganisms Other Alkaloids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
D-Desthiobiotin is a biotin derivative. D-Desthiobiotin increases testosterone. D-Desthiobiotin is used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation .

HY-101884

Biocytin 4 Publications Verification (+)-Biocytin	Human Gut Microbiota Metabolites Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Biocytin is a conjugate of _D-biotin and _L-lysine, where the carboxylate of _D-biotin is coupled with the -amine of _L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .

HY-113409

3-Hydroxyisovaleric acid 1 Publications Verification	Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Cancer Source Classification	Endogenous Metabolite
3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in the urine. The urinary excretion of 3-hydroxyisovaleric acid is early and sensitive indicator of biotin deficiency .

HY-W096159

D-Biotinol	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Drug Derivative
D-Biotinol is an orally active alcohol analogue of D-Biotin (HY-B0511). D-Biotinol can replace D-Biotin to restore the biotin deficiency induced by egg whites in rats. D-Biotinol can be used for the study of biotin deficiency disorders .

HY-N11200

3-Hydroxyisovalerylcarnitine	Natural Products Microorganisms Source Classification	Endogenous Metabolite
3-Hydroxyisovalerylcarnitine is a carnitine derivative. 3-Hydroxyisovaleryl carnitine in plasma may serve as a novel biomarker of biotin deficiency in humans, with its concentration increasing with biotin deficiency. Biotin deficiency reduces the activity of biotin-dependent 3-methylcrotonyl-CoA carboxylase, hinders the conversion of 3-methylcrotonyl-CoA into 3-methylglutaconyl-CoA, and impairs the leucine catabolism pathway; resulting in plasma 3-Hydroxyisovalerylcarnitine concentrations rise .

HY-B0315A

Biotin-Vitamin B12 biotin-Cyanocobalamin B12	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Biotin-Vitamin B12 (Biotin-Cyanocobalamin B12) is the biotinylated Vitamin B12 (HY-B0315). Vitamin B12 is a vitamin that can pass through the blood-brain barrier. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies. Biotin-Vitamin B12 can be used in researches on vitamin B12 transport, cellular uptake, targeted delivery, analytical detection, and other areas .

HY-Y1139

Pimelic acid 2 Publications Verification Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite PROTAC Linkers
Pimelic acid (Heptanedioic acid; 1,5-Pentanedicarboxylic acid) is a seven-carbon α,ω-dicarboxylic acid and a downstream product of fatty acid synthesis. Pimelic acid is a key precursor in biotin biosynthesis. Pimelic acid can be converted to pimelic acid-CoA by the BioW enzyme, thereby bypassing exogenous biotin requirements to support growth in various biotinytrophic bacteria and fungi, and reversing antibiotic-induced inhibition of biotin synthesis. Furthermore, Pimelic acid has been proposed as a highly specific biomarker for oxygen-induced retinopathy in mice. Pimelic acid can be used to study retinopathy of preterm infants, oxygen-induced retinopathy, and microbial biotin metabolism .

HY-113268

Biotin sulfone 2 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Biotin sulfone, a structural analog and metabolite of Biotin (HY-B0511), exerts competitive inhibition against Biotin in Lactobacillus arabinosus 17-5 .

HY-141793

ATRA-biotin biotin-ATRA-conjugate	Alkaloids Classification of Application Fields Other Alkaloids Endogenous metabolite Disease Research Fields Source Classification Cancer	RAR/RXR PPAR Endogenous Metabolite Autophagy
ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue .

HY-B0511R

Biotin (Standard) Vitamin B7 (Standard); Vitamin H (Standard); D-biotin (Standard)	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Reference Standards
Biotin (Standard) is the analytical standard of Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-18341F

Biotin-(L-Thyroxine)	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Thyroid Hormone Receptor Endogenous Metabolite
Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4) .

HY-B0511A

Biotin sodium Vitamin B7 sodium; Vitamin H sodium; D-biotin sodium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Biotin (Vitamin B7) sodium is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin sodium is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-N14664

Actithiazic acid	Structural Classification Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Actithiazic acid is a thiazolidinone antibiotic that targets biotin synthase. Actithiazic acid interferes with essential bacterial metabolism by inhibiting the final step of biotin synthesis (conversion of desthiobiotin to biotin, IC₅₀ = 0.45 μM). Actithiazic acid can be used in studies related to mycobacterial infections .

HY-142080

Pimeloyl-CoA Pimeloyl-coenzyme A	Human Gut Microbiota Metabolites Endogenous metabolite Source Classification	Endogenous Metabolite
Pimeloyl-CoA is a key precursor compound in the biotin synthesis pathway, which can promote the de novo synthesis of biotin. Pimeloyl-CoA is mainly used in the study of microbial metabolic mechanisms, especially the analysis of biotin synthesis pathways and basic research on the biosynthesis of related antibiotics or vitamins .

HY-128699R

D-Desthiobiotin (Standard) Dethiobiotin (Standard)	Alkaloids Human Gut Microbiota Metabolites Microorganisms Other Alkaloids Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
D-Desthiobiotin (Standard) is the analytical standard of D-Desthiobiotin. This product is intended for research and analytical applications. D-Desthiobiotin is a biotin derivative. D-Desthiobiotin increases testosterone. D-Desthiobiotin is used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation .

HY-N15984

*18:1-12:0 Biotin* PC**	Structural Classification Lipid	Liposome
18:1-12:0 Biotin PC can be used in lipid blot analysis for studying the interactions of Niemann-Pick C2 (NPC2)-lipid. 18:1-12:0 Biotin PC is also used to prepare liposomes.

HY-N15978

*18:1-12:0 Biotin* PIP3 tetrasodium**	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin PIP3 tetrasodium is a biotinylated lipid.

HY-113268R

Biotin sulfone (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Biotin sulfone (Standard) is the analytical standard of Biotin sulfone (HY-113268). This product is intended for research and analytical applications. Biotin sulfone, a structural analog and metabolite of Biotin (HY-B0511), exerts competitive inhibition against Biotin in Lactobacillus arabinosus 17-5 .

HY-W741651

Biotin S1P	Lipid	Biochemical Assay Reagents
Biotin S1P is a biotinylated lipid that can be conjugated to streptavidin.

HY-N15974

*18:1-12:0 Biotin* DG**	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin DG is a biotinylated lipid.

HY-N15977

*18:1-6:0 Biotin* PI(3,5)P2 ammonium）**	Lipid	Biochemical Assay Reagents
18:1-6:0 Biotin PI(3,5)P2 ammonium is a biotinylated lipid.

HY-N11200R

3-Hydroxyisovalerylcarnitine (Standard)	Natural Products Microorganisms Source Classification	Endogenous Metabolite Reference Standards
3-Hydroxyisovalerylcarnitine (Standard) is the analytical standard of 3-Hydroxyisovalerylcarnitine. This product is intended for research and analytical applications. 3-Hydroxyisovalerylcarnitine is a carnitine derivative. 3-Hydroxyisovaleryl carnitine in plasma may serve as a novel biomarker of biotin deficiency in humans, with its concentration increasing with biotin deficiency. Biotin deficiency reduces the activity of biotin-dependent 3-methylcrotonyl-CoA carboxylase, hinders the conversion of 3-methylcrotonyl-CoA into 3-methylglutaconyl-CoA, and impairs the leucine catabolism pathway; resulting in plasma 3-Hydroxyisovalerylcarnitine concentrations rise .

HY-101884R

Biocytin (Standard) (+)-Biocytin (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Biocytin (Standard) is the analytical standard of Biocytin. This product is intended for research and analytical applications. Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the -amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays[1][2].

HY-N15878

*Taurocholyl-Lys-Biotin* ammonium**	Lipid	Biochemical Assay Reagents
Taurocholyl-Lys-Biotin ammonium is a biotinylated bile acid.

HY-N15855

*Cholyl-Lys-Biotin* (amminlum)**	Lipid	Biochemical Assay Reagents
Cholyl-Lys-Biotin amminlum is a functionalized bile acid.

HY-N15999

*18:1-12:0 Biotin* PS ammonium**	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin PS ammonium is a biotinylated lipid.

HY-N15970

*18:1-12:0 Biotin* PA ammonium**	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin PA ammonium is a biotinylated form of phosphatidic acid that can be conjugated to streptavidin.

HY-N16001

*18:1-6:0 Biotin* PI(4,5)P2 triammonium**	Lipid	Biochemical Assay Reagents
18:1-6:0 Biotin PI(4,5)P2 triammonium is a biotinylated lipid.

HY-W096159R

D-Biotinol (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Drug Derivative
D-Biotinol (Standard) is the analytical standard of D-Biotinol (HY-W096159). This product is intended for research and analytical applications. D-Biotinol is an orally effective alcohol analogue of D-Biotin (HY-B0511). D-Biotinol can replace D-biotin to restore the biotin deficiency induced by egg whites in rats. D-Biotinol can be used for the study of biotin deficiency disorders.

Cat. No.	Product Name	Chemical Structure

HY-B0511S3

Biotin-13C5
Biotin- ¹³C₅ (Vitamin B7- ¹³C₅) is ¹³C labeled Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids .

HY-B0511S2

Biotin-d2
Biotin-d₂ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-B0511S

Biotin-d2-1
Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-B0511S1

*rel-Biotin-d4*
rel-Biotin-d₄ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-125658S

Biotinyl tyramide-d4
Biotinyl tyramide-d₄ is a deuterated labeled Biotinyl tyramide (HY-125658). Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

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Species:	E.coli (1)
Tag:	His (2)
Source:	E. coli (2)


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Host:	Mouse (2) Donkey (2) Rabbit (6) Goat (7)
Reactivity:	Human (4) Mouse (2) Rat (2) Rabbit (2) Goat (2) Chicken (1) Species independent (2)
Application:	IHC-P (14) ICC/IF (14) IF-Tissue (2) IHC-F (3) WB (14) FC (4) ELISA (15)
Isotype:	IgG (3) IgG1 (1)
Conjugation:	Non-conjugated (3) Biotin (14)
Clonality:	Polyclonal (15) Monoclonal (1)
Modification:	Unmodified (6)


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