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  3. Dox-btn2

Dox-btn2 

Cat. No.: HY-153797 Purity: 97.42%
COA Handling Instructions

Dox-btn2 is a biotinylated derivative of Doxorubicin (HY-15142A), with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm.

For research use only. We do not sell to patients.

Dox-btn2 Chemical Structure

Dox-btn2 Chemical Structure

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1 mg USD 1100 In-stock
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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Dox-btn2 is a biotinylated derivative of Doxorubicin (HY-15142A), with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm[1].

In Vitro

Dox-btn2 (1 μM; 6 h; Exc=531/40 nm and Emi=593/40 nm) exhibits visualization in U2OS cells, helps in situ mapping with Chem-map of small-molecule interactions with DNA and chromatin proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1017.10

Formula

C48H64N4O18S

Appearance

Solid

Color

Brown to orange

SMILES

O=C1C2=C(O)C3=C([C@H](C[C@](C(CO)=O)(C3)O)O[C@H]4C[C@H](NC(CCOCCOCCOCCOCCNC(CCCC[C@H]5[C@@]6([H])NC(N[C@]6(CS5)[H])=O)=O)=O)[C@H](O)[C@H](C)O4)C(O)=C2C(C7=C1C=CC=C7OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dox-btn2
Cat. No.:
HY-153797
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