Dox-btn2
Based on 1 Customer Validation
Dox-btn2 is a biotin labeled Doxorubicin (HY-15142A), with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm.
For research use only. We do not sell to patients.
- Purity: 98.80%
- CAS No.: 3026061-31-1
- Formula: C48H64N4O18S
- Molecular Weight:1017.10
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Dox-btn2 (1 μM; 6 h; Exc=531/40 nm and Emi=593/40 nm) exhibits visualization in U2OS cells, helps in situ mapping with Chem-map of small-molecule interactions with DNA and chromatin proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3026061-31-1
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Appearance Solid
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Molecular Weight 1017.10
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Formula C48H64N4O18S
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Color Brown to orange
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SMILES
O=C1C2=C(O)C3=C([C@H](C[C@](C(CO)=O)(C3)O)O[C@H]4C[C@H](NC(CCOCCOCCOCCOCCNC(CCCC[C@H]5[C@@]6([H])NC(N[C@]6(CS5)[H])=O)=O)=O)[C@H](O)[C@H](C)O4)C(O)=C2C(C7=C1C=CC=C7OC)=O
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Synonyms
Biotin Labeled Doxorubicin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 50 mg/mL (49.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9832 mL | 4.9159 mL | 9.8319 mL | 24.5797 mL |
| 5 mM | 0.1966 mL | 0.9832 mL | 1.9664 mL | 4.9159 mL | |
| 10 mM | 0.0983 mL | 0.4916 mL | 0.9832 mL | 2.4580 mL | |
| 15 mM | 0.0655 mL | 0.3277 mL | 0.6555 mL | 1.6386 mL | |
| 20 mM | 0.0492 mL | 0.2458 mL | 0.4916 mL | 1.2290 mL | |
| 25 mM | 0.0393 mL | 0.1966 mL | 0.3933 mL | 0.9832 mL | |
| 30 mM | 0.0328 mL | 0.1639 mL | 0.3277 mL | 0.8193 mL | |
| 40 mM | 0.0246 mL | 0.1229 mL | 0.2458 mL | 0.6145 mL |
Dox-btn2 Related Classifications
HY-153797 Related Classifications
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