1. PROTAC
  2. PROTAC Linker
  3. Biotin-PEG2-C2-iodoacetamide

Biotin-PEG2-C2-iodoacetamide 

Cat. No.: HY-140941
Handling Instructions

Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Biotin-PEG2-C2-iodoacetamide Chemical Structure

Biotin-PEG2-C2-iodoacetamide Chemical Structure

CAS No. : 292843-75-5

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Description

Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

542.43

Formula

C₁₈H₃₁IN₄O₅S

CAS No.

292843-75-5

SMILES

O=C(NCCOCCOCCNC(CI)=O)CCCC[[email protected]@H]1SC[[email protected]]([[email protected]]1([H])N2)([H])NC2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

Biotin-PEG2-C2-iodoacetamidePROTAC LinkerInhibitorinhibitorinhibit

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Product Name:
Biotin-PEG2-C2-iodoacetamide
Cat. No.:
HY-140941
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