Biotin-Thalidomide
Based on 1 Customer Validation
Biotin-Thalidomide is a biotin-conjugated Thalidomide (HY-14658) for binding to CRBN. Biotin-Thalidomide can be used to synthesize PROTAC .
For research use only. We do not sell to patients.
- Purity: 99.45%
- CAS No.: 2230857-87-9
- Formula: C44H64N8O13S
- Molecular Weight:945.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2230857-87-9
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Appearance Solid
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Molecular Weight 945.09
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Formula C44H64N8O13S
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Color Off-white to yellow
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SMILES
O=C1C2=C(OCC(NCCCCNC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]3[C@]4([H])[C@](NC(N4)=O)([H])CS3)=O)=O)=O)=O)C=CC=C2C(N1C5C(NC(CC5)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Methanol : 125 mg/mL (132.26 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 1.0581 mL | 5.2905 mL | 10.5810 mL | 26.4525 mL |
| 5 mM | 0.2116 mL | 1.0581 mL | 2.1162 mL | 5.2905 mL | |
| 10 mM | 0.1058 mL | 0.5291 mL | 1.0581 mL | 2.6453 mL | |
| 15 mM | 0.0705 mL | 0.3527 mL | 0.7054 mL | 1.7635 mL | |
| 20 mM | 0.0529 mL | 0.2645 mL | 0.5291 mL | 1.3226 mL | |
| 25 mM | 0.0423 mL | 0.2116 mL | 0.4232 mL | 1.0581 mL | |
| 30 mM | 0.0353 mL | 0.1764 mL | 0.3527 mL | 0.8818 mL | |
| 40 mM | 0.0265 mL | 0.1323 mL | 0.2645 mL | 0.6613 mL | |
| 50 mM | 0.0212 mL | 0.1058 mL | 0.2116 mL | 0.5291 mL | |
| 60 mM | 0.0176 mL | 0.0882 mL | 0.1764 mL | 0.4409 mL | |
| 80 mM | 0.0132 mL | 0.0661 mL | 0.1323 mL | 0.3307 mL | |
| 100 mM | 0.0106 mL | 0.0529 mL | 0.1058 mL | 0.2645 mL |
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