18:0 mPEG550 PE ammonium
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
For research use only. We do not sell to patients.
- CAS No.: 474922-77-5
- Formula: (C2H4O)nC43H84NO10P.H3N
- Molecular Weight:550(Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 474922-77-5
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Molecular Weight 550(Average)
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Formula (C2H4O)nC43H84NO10P.H3N
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SMILES
O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O)OCCOC.N.[n]
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Synonyms
DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Anatoly N Lukyanov, et al. Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits. J Control Release. 2004 Jan 8;94(1):187-93. [Content Brief]
[2]. Cooper A, et al. Osmotic Pressure Enables High-Yield Assembly of Giant Vesicles in Solutions of Physiological Ionic Strengths. Langmuir. 2023 Apr 18;39(15):5579-5590. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)