2-(Biotin-amido)-1,3-bis-(C1-PEG1-acid)
2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 2086689-02-1
- Formula: C19H31N3O8S
- Molecular Weight:461.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTAC Linkers Isoforms
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Biological Activity
Description
IC50 & Target
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PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2086689-02-1
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Molecular Weight 461.53
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Formula C19H31N3O8S
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SMILES
O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(NC(COCCC(O)=O)COCCC(O)=O)=O)[H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)