18:0 mPEG2000 PE  (Synonyms: DSPE-mPEG2000; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000])

18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG2000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (2 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG2000 PE ammonium can be used for the research of nanoprobes and drug delivery^[1][2][3][4].

18:0 mPEG2000 PE ammonium is used to synthesize a highly sensitive and selective fluorescent probe (BANP) for detecting dibutyl phthalate (DBP)^[1].
18:0 mPEG2000 PE ammonium is used to prepare near-infrared II (NIR-II) scaffold molecular dye (SYL) and to prepare it into a nanoprobe for tumor imaging and photothermal therapy^[2].
18:0 mPEG2000 PE ammonium is used to synthesize organic nanoparticles targeting lysosomes for photoacoustic imaging and photodynamic anticancer research under near-infrared light^[3].
18:0 mPEG2000 PE ammonium is used to develop a nanoprobe based on a platinum (II) metal ring in the second near-infrared region (NIR-II), integrating fluorescence imaging and chemotherapy^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2000(Average)

(C₂H₄O)_nC₄₃H₈₄NO₁₀P

156543-00-9

Solid

White to off-white

O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O)OCCOC.[n]

Room temperature in continental US; may vary elsewhere.

• [1]. Lu JY, et al. A dye-andrographolide assembly as a turn-on sensor for detection of phthalate in both cells and fish. Anal Chim Acta. 2022 Feb 22;1195:339460.  [Content Brief]

  [2]. Zhang R, et al. Rational design of a multifunctional molecular dye for dual-modal NIR-II/photoacoustic imaging and photothermal therapy. Chem Sci. 2019 Jul 30;10(36):8348-8353.  [Content Brief]

  [3]. Hu W, et al. Engineering Lysosome-Targeting BODIPY Nanoparticles for Photoacoustic Imaging and Photodynamic Therapy under Near-Infrared Light. ACS Appl Mater Interfaces. 2016 May 18;8(19):12039-47.  [Content Brief]

  [4]. Sun Y, et al. Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1968-1973.  [Content Brief]