1. PROTAC
  2. PROTAC Linker
  3. Biotin-bis-amido-SS-NHS

Biotin-bis-amido-SS-NHS 

Cat. No.: HY-130490
Handling Instructions

Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Biotin-bis-amido-SS-NHS Chemical Structure

Biotin-bis-amido-SS-NHS Chemical Structure

CAS No. : 142439-92-7

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All PROTAC Linker Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

Alkyl/ether

 

In Vitro

Biotin-bis-amido-SS-NHS is a long arm biotin containing disulfide bond, and the compound can be applied to biochemistry detection field, reduce the influence of steric effect, improve the sensitivity of detection[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Molecular Weight

575.72

Formula

C₂₂H₃₃N₅O₇S₃

CAS No.

142439-92-7

SMILES

O=C(NCCNC(CCSSCCC(ON1C(CCC1=O)=O)=O)=O)CCCC[[email protected]@H]2SC[[email protected]]([[email protected]]2([H])N3)([H])NC3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Biotin-bis-amido-SS-NHSPROTAC LinkerProtaclinkercancerPEGbiotinInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Biotin-bis-amido-SS-NHS
Cat. No.:
HY-130490
Quantity:
MCE Japan Authorized Agent: