PC Biotin-PEG3-azide
Based on 1 Customer Validation
PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity: 97.75%
- CAS No.: 1937270-46-6
- Formula: C35H55N9O12S
- Molecular Weight:825.93
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1937270-46-6
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Appearance Oil
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Molecular Weight 825.93
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Formula C35H55N9O12S
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Color Colorless to light yellow
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SMILES
O=C(OC(C1=CC(OC)=C(OCCCC(NCCOCCOCCOCCNC(CCCC[C@H]2SC[C@@]([C@@]2([H])N3)([H])NC3=O)=O)=O)C=C1[N+]([O-])=O)C)NCCCN=[N+]=[N-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (60.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (466 KB)
- English - EN (466 KB)
- Français - FR (466 KB)
- Deutsch - DE (466 KB)
- Norwegian - NO (466 KB)
- Español - ES (466 KB)
- Swedish - SV (466 KB)
- Italian - IT (466 KB)
- Korean - KR (466 KB)
- Portuguese - PT (466 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2108 mL | 6.0538 mL | 12.1076 mL | 30.2689 mL |
| 5 mM | 0.2422 mL | 1.2108 mL | 2.4215 mL | 6.0538 mL | |
| 10 mM | 0.1211 mL | 0.6054 mL | 1.2108 mL | 3.0269 mL | |
| 15 mM | 0.0807 mL | 0.4036 mL | 0.8072 mL | 2.0179 mL | |
| 20 mM | 0.0605 mL | 0.3027 mL | 0.6054 mL | 1.5134 mL | |
| 25 mM | 0.0484 mL | 0.2422 mL | 0.4843 mL | 1.2108 mL | |
| 30 mM | 0.0404 mL | 0.2018 mL | 0.4036 mL | 1.0090 mL | |
| 40 mM | 0.0303 mL | 0.1513 mL | 0.3027 mL | 0.7567 mL | |
| 50 mM | 0.0242 mL | 0.1211 mL | 0.2422 mL | 0.6054 mL | |
| 60 mM | 0.0202 mL | 0.1009 mL | 0.2018 mL | 0.5045 mL |
PC Biotin-PEG3-azide Related Classifications
HY-140132 Related Classifications
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