Glucose-PEG1000-Biotin
Glucose-PEG1000-Biotin is a conjugate composed of glucose, PEG chains, and biotin. Glucose-PEG1000-Biotin combines the targeted recognition capabilities of glucose with the high-affinity binding ability of biotin to avidin/streptavidin, enabling applications such as targeted drug delivery systems and nanoparticle modification.
For research use only. We do not sell to patients.
- Molecular Weight:1000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
The structure of Glucose-PEG-Biotin comprises three key components that work synergistically:
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), achieving receptor-mediated active targeted delivery.
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo.
Biotin: Located at the end of the PEG chain, it serves as a reaction interface with high non-covalent binding affinity to avidin or streptavidin, and is widely used in signal amplification and molecular capture.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1000 (Average)
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SMILES
OC1O[C@H]([C@@H]([C@H]([C@@H]1NC(OCCOCCNC(CCCCC2[C@](NC(N3)=O)([H])[C@]3([H])CS2)=O)=O)O)O)CO.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)