Biotin-PEG8-alcohol
Based on 1 Customer Validation
Biotin-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 97.16%
- CAS No.: 2182601-20-1
- Formula: C26H49N3O10S
- Molecular Weight:595.75
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2182601-20-1
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Appearance Oil
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Molecular Weight 595.75
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Formula C26H49N3O10S
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Color Colorless to off-white
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SMILES
O=C(NCCOCCOCCOCCOCCOCCOCCOCCO)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (419.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6786 mL | 8.3928 mL | 16.7856 mL | 41.9639 mL |
| 5 mM | 0.3357 mL | 1.6786 mL | 3.3571 mL | 8.3928 mL | |
| 10 mM | 0.1679 mL | 0.8393 mL | 1.6786 mL | 4.1964 mL | |
| 15 mM | 0.1119 mL | 0.5595 mL | 1.1190 mL | 2.7976 mL | |
| 20 mM | 0.0839 mL | 0.4196 mL | 0.8393 mL | 2.0982 mL | |
| 25 mM | 0.0671 mL | 0.3357 mL | 0.6714 mL | 1.6786 mL | |
| 30 mM | 0.0560 mL | 0.2798 mL | 0.5595 mL | 1.3988 mL | |
| 40 mM | 0.0420 mL | 0.2098 mL | 0.4196 mL | 1.0491 mL | |
| 50 mM | 0.0336 mL | 0.1679 mL | 0.3357 mL | 0.8393 mL | |
| 60 mM | 0.0280 mL | 0.1399 mL | 0.2798 mL | 0.6994 mL | |
| 80 mM | 0.0210 mL | 0.1049 mL | 0.2098 mL | 0.5245 mL | |
| 100 mM | 0.0168 mL | 0.0839 mL | 0.1679 mL | 0.4196 mL |
Biotin-PEG8-alcohol Related Classifications
HY-140894 Related Classifications
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