TCO-PEG3-Biotin
Based on 1 Customer Validation
TCO-PEG3-Biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). TCO-PEG3-Biotin is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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- Pureza: 99.41%
- No. CAS: 2098630-62-5
- Fòrmula: C27H46N4O7S
- Peso molecular:570.74
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2098630-62-5
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Appearance Solid
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Peso molecular 570.74
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Fòrmula C27H46N4O7S
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Color White to off-white
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SMILES
O=C(NCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@H](N2)[C@@H]1NC2=O)=O)O[C@H]3CCC/C([H])=C/CC3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 125 mg/mL (219.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7521 mL | 8.7606 mL | 17.5211 mL | 43.8028 mL |
| 5 mM | 0.3504 mL | 1.7521 mL | 3.5042 mL | 8.7606 mL | |
| 10 mM | 0.1752 mL | 0.8761 mL | 1.7521 mL | 4.3803 mL | |
| 15 mM | 0.1168 mL | 0.5840 mL | 1.1681 mL | 2.9202 mL | |
| 20 mM | 0.0876 mL | 0.4380 mL | 0.8761 mL | 2.1901 mL | |
| 25 mM | 0.0701 mL | 0.3504 mL | 0.7008 mL | 1.7521 mL | |
| 30 mM | 0.0584 mL | 0.2920 mL | 0.5840 mL | 1.4601 mL | |
| 40 mM | 0.0438 mL | 0.2190 mL | 0.4380 mL | 1.0951 mL | |
| 50 mM | 0.0350 mL | 0.1752 mL | 0.3504 mL | 0.8761 mL | |
| 60 mM | 0.0292 mL | 0.1460 mL | 0.2920 mL | 0.7300 mL | |
| 80 mM | 0.0219 mL | 0.1095 mL | 0.2190 mL | 0.5475 mL | |
| 100 mM | 0.0175 mL | 0.0876 mL | 0.1752 mL | 0.4380 mL |
TCO-PEG3-Biotin Related Classifications
HY-136050 Related Classifications
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