1. Biochemical Assay Reagents

ATP-polyamine-biotin 

Cat. No.: HY-D0183 Purity: 98.99%
Handling Instructions

APB is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues.

For research use only. We do not sell to patients.
ATP-polyamine-biotin Chemical Structure

ATP-polyamine-biotin Chemical Structure

CAS No. : 1800401-93-7

Size Price Stock Quantity
1 mg USD 540 In-stock
2 mg USD 960 In-stock
5 mg USD 1680 In-stock
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

APB is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM. APB is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. APB is cell-permeable and nontoxic at low mM concentrations, with cell penetration and labeling dependent on the polyamine linker.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.0573 mL 5.2863 mL 10.5725 mL
5 mM 0.2115 mL 1.0573 mL 2.1145 mL
10 mM 0.1057 mL 0.5286 mL 1.0573 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

945.85

Formula

C₃₂H₅₈N₁₁O₁₄P₃S

CAS No.

1800401-93-7

SMILES

O=C(CCCC[[email protected]@H]1SC[[email protected]]([[email protected]]1([H])N2)([H])NC2=O)NCCCN(C)CCCCN(C)CCCNP(O)(OP(O)(OP(O)(OC[[email protected]@H]3[[email protected]@H](O)[[email protected]@H](O)[[email protected]](N4C(N=CN=C5N)=C5N=C4)O3)=O)=O)=O

Storage

4°C, protect from light

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

H2O: 6 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
ATP-polyamine-biotin
Cat. No.:
HY-D0183
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