18:0 mPEG5000 PE ammonium
Based on 1 Customer Validation
18:0 mPEG5000 PE (DSPE-mPEG5000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG5000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (5 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG5000 PE ammonium can be used for the research of nanoprobes and drug delivery.
For research use only. We do not sell to patients.
- Purity: 99%
- CAS No.: 474922-77-5
- Formula: (C2H4O)nC43H84NO10P.H3N
- Molecular Weight:5000(Average)
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
18:0 mPEG5000 PE ammonium was used to synthesize a highly sensitive and selective fluorescent probe (BANP) for detecting dibutyl phthalate (DBP)[1].
18:0 mPEG5000 PE ammonium was used to prepare near-infrared II (NIR-II) scaffold molecular dye (SYL) and to prepare it into a nanoprobe for tumor imaging and photothermal therapy[2].
18:0 mPEG5000 PE ammonium was used to synthesize organic nanoparticles targeting lysosomes for photoacoustic imaging and photodynamic anticancer research under near-infrared light[3].
18:0 mPEG5000 PE ammonium was used to develop a nanoprobe based on a platinum (II) metal ring in the second near-infrared region (NIR-II), integrating fluorescence imaging and chemotherapy[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 474922-77-5
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Appearance Solid
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Molecular Weight 5000(Average)
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Formula (C2H4O)nC43H84NO10P.H3N
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Color White to off-white
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SMILES
O=C(NCCOP(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O)OCCOC.N.[n]
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Synonyms
DSPE-mPEG5000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (585 KB)
- English - EN (585 KB)
- Français - FR (585 KB)
- Deutsch - DE (585 KB)
- Norwegian - NO (585 KB)
- Español - ES (585 KB)
- Swedish - SV (585 KB)
- Italian - IT (585 KB)
- Korean - KR (585 KB)
- Portuguese - PT (585 KB)
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Handling Instructions (2659 KB)
References
[1]. Lu JY, et al. A dye-andrographolide assembly as a turn-on sensor for detection of phthalate in both cells and fish. Anal Chim Acta. 2022 Feb 22;1195:339460. [Content Brief]
[2]. Zhang R, et al. Rational design of a multifunctional molecular dye for dual-modal NIR-II/photoacoustic imaging and photothermal therapy. Chem Sci. 2019 Jul 30;10(36):8348-8353. [Content Brief]
[3]. Hu W, et al. Engineering Lysosome-Targeting BODIPY Nanoparticles for Photoacoustic Imaging and Photodynamic Therapy under Near-Infrared Light. ACS Appl Mater Interfaces. 2016 May 18;8(19):12039-47. [Content Brief]
[4]. Sun Y, et al. Rhomboidal Pt(II) metallacycle-based NIR-II theranostic nanoprobe for tumor diagnosis and image-guided therapy. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1968-1973. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
18:0 mPEG5000 PE ammonium Related Classifications
HY-144013H Related Classifications
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