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  3. Mannose-PEG10000-Biotin

Mannose-PEG10000-Biotin is a conjugate composed of mannose, PEG chains, and biotin. Mannose-PEG-Biotin combines the targeting recognition ability of mannose with the high affinity of biotin to bind avidin/link avidin, and is used for applications such as constructing targeted drug delivery systems and nanoparticle modification.

For research use only. We do not sell to patients.

Mannose-PEG10000-Biotin

Mannose-PEG10000-Biotin Chemical Structure

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Description

Mannose-PEG10000-Biotin is a conjugate composed of mannose, PEG chains, and biotin. Mannose-PEG-Biotin combines the targeting recognition ability of mannose with the high affinity of biotin to bind avidin/link avidin, and is used for applications such as constructing targeted drug delivery systems and nanoparticle modification.

In Vitro

The structure of Mannose-PEG-Biotin contains three key parts that work synergistically:
Mannose: As a targeting navigator, it can specifically recognize and bind to mannose receptors on the cell surface.
PEG chain: As a hydrophilic spacer arm, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
Biotin: Located at the end of the PEG chain, it is the reaction interface and has a high non-covalent affinity for avidin or streptavidin, widely used in signal amplification and molecular capture.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SMILES

OC[C@@H]1OC(O)[C@H](NC(OCCOCCNC(CCCCC2[C@](NC(N3)=O)([H])[C@]3([H])CS2)=O)=O)[C@H](O)[C@H]1O.[n]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mannose-PEG10000-Biotin
Cat. No.:
HY-182981D
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