1. Acids and Aldehydes
  2. Biotin

Biotin (Synonyms: Vitamin B7; Vitamin H; D-Biotin)

Cat. No.: HY-B0511 Purity: 99.80%
Handling Instructions

Biotin is an enzyme co-factor present in minute amounts in every living cell.

For research use only. We do not sell to patients.

Biotin Chemical Structure

Biotin Chemical Structure

CAS No. : 58-85-5

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g USD 84 In-stock
Estimated Time of Arrival: December 31
5 g USD 300 In-stock
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Customer Review

Based on 3 publication(s) in Google Scholar

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Description

Biotin is an enzyme co-factor present in minute amounts in every living cell. Target: Others Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the citric acid cycle, which is the process by which biochemical energy is generated during aerobic respiration. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. In addition, biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. The dietary biotin intake in Western populations has been estimated to be 35 to 70 microg/d (143-287 nmol/d). Recent studies suggest that humans absorb biotin nearly completely. Conditions that may increase biotin requirements in humans include pregnancy, lactation, and therapy with anticonvulsants or lipoic acid [1, 2].

Clinical Trial
Molecular Weight

244.31

Formula

C₁₀H₁₆N₂O₃S

CAS No.

58-85-5

SMILES

O=C(O)CCCC[[email protected]@H]1SC[[email protected]]([[email protected]]1([H])N2)([H])NC2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 41.67 mg/mL (170.56 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0932 mL 20.4658 mL 40.9316 mL
5 mM 0.8186 mL 4.0932 mL 8.1863 mL
10 mM 0.4093 mL 2.0466 mL 4.0932 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (8.51 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (8.51 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (8.51 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.80%

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

BiotinVitamin B7Vitamin HD-BiotinVitamin B 7Vitamin B-7OthersInhibitorinhibitorinhibit

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