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Trolox

36 Cited Publications
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Based on 36 publication(s) in Google Scholar

Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage.

For research use only. We do not sell to patients.

  • Purity: 99.90%
  • CAS No.: 53188-07-1
  • Formula: C14H18O4
  • Molecular Weight:250.29
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Trolox Chemical Structure
    Trolox Chemical Structure
  • Experimental Validation Results for Trolox
  • Experimental Validation Results for Trolox
  • Experimental Validation Results for Trolox
  • Experimental Validation Results for Trolox
CAS No.: 53188-07-1
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[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Cell Proliferation/Viability AssayBio/Physico-chemical AssayFlow CytometryWB
  • Cell Proliferation/Viability Assay
  • Bio/Physico-chemical Assay
  • Flow Cytometry
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  • Trolox Chemical Structure
    Trolox Chemical Structure
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    Trolox purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 7:e09208. [Abstract]

    Customer Validation
     Trolox (100 µM), a hydrophilic analogue of VE with potent antioxidant effect, was used as a control of VE. After a short incubation time of 6 h, cathepsin inhibitors (CA‐074, Pep‐A, and E‐64), Ca2+ chelator, and cellular ROS scavengers (NAC, VC, and Trolox) displayed a delayed effect of ipLNP cytotoxicity.

  • 1/16

    Trolox purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2025 Oct 6;11(1):430. [Abstract]

    Customer Validation
     Trolox (5 µM) also rescued TNBC cells from cystine deprivation-induced cell death by reducing ROS levels. Representative images of Hs578Ts(i)8 and SUM159 cells treated with Trolox and/or glutamine deprivation under cystine-deprived conditions.

  • 1/16

    Trolox purchased from MedChemExpress. Usage Cited in: Cell Rep. 2022 Oct 11;41(2):111462. [Abstract]

    Customer Validation
     With an alternative ROS scavenger, the vitamin E analog Trolox, Olaparib-induced ROS production was similarly suppressed

  • 1/16

    Trolox purchased from MedChemExpress. Usage Cited in: Oxid Med Cell Longev. 2020 Jan 27;2020:5829521. [Abstract]

    Customer Validation
     The effects of Trolox on the expression of Nrf2 and its downstream targets. MDBK cells in 60 mm dishes pretreated with Trolox (1 mM) or DMSO control for 1 h are exposed to tBHP in the presence of Trolox or DMSO control for 2 h; the cell lysates are prepared for Western blots to detect the expression of Nrf2 and HO-1.

  • Trolox