58-85-5
Chemical Structure
Biotin
Synonym(s): Vitamin B7; Vitamin H; D-Biotin
- CAS No.: 58-85-5
- Formula:C10H16N2O3S
- Molecular Weight:244.31
IUPAC Name: 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid
InChIKey: YBJHBAHKTGYVGT-ZKWXMUAHSA-N
SMILES: O=C(O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
Biological Activity: Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids[1][2][3].
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Biotin | 99.16% | Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. | ||||||||||||||||||||
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Biotin (Standard) | 99.81% | Biotin (Standard) is the analytical standard of Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. | ||||||||||||||||||||
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Biotin-d2-1 | 99.65% | Biotin-d2-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell. | ||||||||||||||||||||
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Biotin-13C5 | Biotin-13C5 (Vitamin B7-13C5) is 13C labeled Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. | |||||||||||||||||||||
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rel-Biotin-d4 | 98.04% | rel-Biotin-d4 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell. | ||||||||||||||||||||
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Biotin-d2 | 98.53% | Biotin-d2 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell. | ||||||||||||||||||||
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Biotin Hydrazide | 99.58% | Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe. | ||||||||||||||||||||
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Biotin Hydrazide (Standard) | ≥98% | Biotin Hydrazide (Standard) is the analytical standard of Biotin Hydrazide (HY-100215). This product is intended for research and analytical applications. Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe. | ||||||||||||||||||||
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2-Iminobiotin | 99.95% | 2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage. | ||||||||||||||||||||
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2-Iminobiotin hydrobromide (Standard) | ≥98% | 2-Iminobiotin hydrobromide (Standard) (Guanidinobiotin hydrobromide (Standard)) is the analytical standard of 2-Iminobiotin hydrobromide (HY-118700A). This product is intended for research and analytical applications. 2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage. | ||||||||||||||||||||
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Biotin-EDA | 99.76% | Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Biotin alkyne | 99.53% | Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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(±)-Biotin sulfoxide | (±)-Biotin sulfoxide is a racemic mixture of the Biotin sulfoxide (HY-W129869). | |||||||||||||||||||||
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Biotin sodium | Biotin (Vitamin B7) sodium is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin sodium is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. | |||||||||||||||||||||
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L-Biotin | 99.52% | L-Biotin is the unnatural enantiomer of Biotin (HY-B0511). | ||||||||||||||||||||
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Biotin methyl ester | 99.60% | Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Biotin sulfoxide | Biotin sulfoxide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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N-Biotinyl-4-aminobutanoic acid | N-Biotinyl-4-aminobutanoic acid is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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rel-Biotin methyl ester | rel-Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Biotin-d-sulfoxide | Biotin-d-sulfoxide is an active compound. | |||||||||||||||||||||
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References
- [1]. Zempleni, et al. Biotin biochemistry and human requirements. J Nutr Biochem, 1999. 10(3): p. 128-38. [Content Brief]
- [2]. Mock, D.M.. Biotin status: which are valid indicators and how do we know? J Nutr, 1999. 129(2S Suppl): p. 498S-503S. [Content Brief]
- [3]. Zempleni J, et al. Biotin. Biofactors. 2009 Jan-Feb;35(1):36-46. [Content Brief]