1. Immunology/Inflammation
  2. NO Synthase
  3. 2-Iminobiotin

2-Iminobiotin (Synonyms: Guanidinobiotin)

Cat. No.: HY-118700 Purity: >98.0%
Handling Instructions

2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage.

For research use only. We do not sell to patients.

2-Iminobiotin Chemical Structure

2-Iminobiotin Chemical Structure

CAS No. : 13395-35-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].

IC50 & Target

Nitric oxide synthases[1]

Molecular Weight

243.33

Formula

C₁₀H₁₇N₃O₂S

CAS No.

13395-35-2

SMILES

[H][[email protected]](CS[[email protected]]1CCCCC(O)=O)([[email protected]]1([H])N2)NC2=N

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (51.37 mM; Need ultrasonic)

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1096 mL 20.5482 mL 41.0965 mL
5 mM 0.8219 mL 4.1096 mL 8.2193 mL
10 mM 0.4110 mL 2.0548 mL 4.1096 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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2-Iminobiotin
Cat. No.:
HY-118700
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