1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Biotin sodium

Biotin sodium  (Synonyms: Vitamin B7 sodium; Vitamin H sodium; D-Biotin sodium)

Cat. No.: HY-B0511A
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Biotin (Vitamin B7) sodium is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin sodium is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.

For research use only. We do not sell to patients.

CAS No. : 56085-82-6

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Top Publications Citing Use of Products

    Biotin sodium purchased from MedChemExpress. Usage Cited in: Acta Pharm Sin B. 2025 Apr;15(4):1974-1990.

    Immunoblotting was performed to detect the presence of ADCY10 following co-incubation with cell lysate and subsequent precipitation of bound protein using streptavidin magnetic beads with either Bio-OLCarn or Biotin (20 mmol/L) for 12 h at 4 °C with continuous rotation.

    Biotin sodium purchased from MedChemExpress. Usage Cited in: Acta Pharm Sin B. 2025 Apr;15(4):1974-1990.

    Fluorescence intensity represents the colocalization of ADCY10 and Bio-OLCarn or Biotin (20 mmol/L) in HCC1806 cells overnight at 4 ℃; green: ADCY10, red: Bio-OLCarn.

    Biotin sodium purchased from MedChemExpress. Usage Cited in: J Clin Invest. 2025 Mar 17;135(6):e185278.  [Abstract]

    Biotin pull-down assay. SW620 cell protein lysates were incubated with biotin, biotin-RLY01 (B-RLY01; 10 μM), B-RLY01 (10 μM) + 100 μM RLY01 (10× molar excess), B-RLY01 (10 μM) + 200 μM RLY01 (20× molar excess) at room temperature for 3 hours by rotation.

    Biotin sodium purchased from MedChemExpress. Usage Cited in: Cell Discov. 2025 Sep 30;11(1):80.

    Biotin (50 μM, 3 h). MDA-MB-231 cells were treated with indicated drugs for 3 h, and biotin was pulled down. Interacting proteins were stained with Coomassie brilliant blue and K48 polyUB was detected by western blotting

    Biotin sodium purchased from MedChemExpress. Usage Cited in: Theranostics. 2020 May 22;10(15):6839-6853.  [Abstract]

    Immunoblot with anti-NCOR2, anti-ACACA, anti-FASN, anti-CAD, and anti-α-Tubulin antibodies of protein precipitated by streptavidin beads from MDA-MB-231 cell lysates in the presence of B-Emodin or Biotin (10 µM) for 5 h at 4 ℃ with rotation.

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    Description

    Biotin (Vitamin B7) sodium is a water-soluble B vitamin and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin sodium is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids[1][2][3].

    IC50 & Target

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    Clinical Trial
    Molecular Weight

    266.29

    Formula

    C10H15N2NaO3S

    CAS No.
    SMILES

    O=C(O[Na])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
    References
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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Biotin sodium
    Cat. No.:
    HY-B0511A
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