Cholic acid-Biotin
Based on 1 Customer Validation
Cholic acid-Biotin is a biotin-labeled Cholic acid (HY-N0324). Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid has orally activity.
For research use only. We do not sell to patients.
- Purity: 95.0%
- Formula: C42H72N4O9S
- Molecular Weight:809.11
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 809.11
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Formula C42H72N4O9S
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Color White to off-white
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SMILES
O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(NCCOCCOCCOCCNC(CC[C@@H](C)[C@@]3([H])CC[C@@]4([H])[C@]5([H])[C@H](O)C[C@]6([H])C[C@@H](CC[C@]6(C)[C@@]5([H])C[C@H](O)[C@]34C)O)=O)=O)N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (123.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Li Y, et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684. [Content Brief]
[2]. Pan X, et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2359 mL | 6.1796 mL | 12.3593 mL | 30.8981 mL |
| 5 mM | 0.2472 mL | 1.2359 mL | 2.4719 mL | 6.1796 mL | |
| 10 mM | 0.1236 mL | 0.6180 mL | 1.2359 mL | 3.0898 mL | |
| 15 mM | 0.0824 mL | 0.4120 mL | 0.8240 mL | 2.0599 mL | |
| 20 mM | 0.0618 mL | 0.3090 mL | 0.6180 mL | 1.5449 mL | |
| 25 mM | 0.0494 mL | 0.2472 mL | 0.4944 mL | 1.2359 mL | |
| 30 mM | 0.0412 mL | 0.2060 mL | 0.4120 mL | 1.0299 mL | |
| 40 mM | 0.0309 mL | 0.1545 mL | 0.3090 mL | 0.7725 mL | |
| 50 mM | 0.0247 mL | 0.1236 mL | 0.2472 mL | 0.6180 mL | |
| 60 mM | 0.0206 mL | 0.1030 mL | 0.2060 mL | 0.5150 mL | |
| 80 mM | 0.0154 mL | 0.0772 mL | 0.1545 mL | 0.3862 mL | |
| 100 mM | 0.0124 mL | 0.0618 mL | 0.1236 mL | 0.3090 mL |