Cholic acid-Biotin

Cat. No.: HY-N0324F Purity: 95.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Cholic acid-Biotin is a biotin-labeled Cholic acid (HY-N0324). Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid has orally activity.

For research use only. We do not sell to patients.

Cholic acid-Biotin Chemical Structure

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Cholic acid-Biotin:

Cholic acid In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

809.11

Formula

C₄₂H₇₂N₄O₉S

Appearance

Solid

Color

White to off-white

SMILES

O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(NCCOCCOCCOCCNC(CC[C@@H](C)[C@@]3([H])CC[C@@]4([H])[C@]5([H])[C@H](O)C[C@]6([H])C[C@@H](CC[C@]6(C)[C@@]5([H])C[C@H](O)[C@]34C)O)=O)=O)N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (123.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2359 mL	6.1796 mL	12.3593 mL
5 mM	0.2472 mL	1.2359 mL	2.4719 mL
10 mM	0.1236 mL	0.6180 mL	1.2359 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.0%

Select Batch:

Data Sheet (266 KB) SDS (252 KB)

COA (243 KB) HNMR (313 KB)

Handling Instructions (2659 KB)

References

[1]. Li Y, et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684. [Content Brief]

[2]. Pan X, et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.2359 mL	6.1796 mL	12.3593 mL	30.8981 mL
	5 mM	0.2472 mL	1.2359 mL	2.4719 mL	6.1796 mL
	10 mM	0.1236 mL	0.6180 mL	1.2359 mL	3.0898 mL
	15 mM	0.0824 mL	0.4120 mL	0.8240 mL	2.0599 mL
	20 mM	0.0618 mL	0.3090 mL	0.6180 mL	1.5449 mL
	25 mM	0.0494 mL	0.2472 mL	0.4944 mL	1.2359 mL
	30 mM	0.0412 mL	0.2060 mL	0.4120 mL	1.0299 mL
	40 mM	0.0309 mL	0.1545 mL	0.3090 mL	0.7725 mL
	50 mM	0.0247 mL	0.1236 mL	0.2472 mL	0.6180 mL
	60 mM	0.0206 mL	0.1030 mL	0.2060 mL	0.5150 mL
	80 mM	0.0154 mL	0.0772 mL	0.1545 mL	0.3862 mL
	100 mM	0.0124 mL	0.0618 mL	0.1236 mL	0.3090 mL