Biotin-C5-Azide
Based on 1 Customer Validation
Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates. Biotin-C5-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity: 98.92%
- CAS No.: 1260586-88-6
- Formula: C10H17N5OS
- Molecular Weight:255.34
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension—Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1260586-88-6
-
Appearance Solid
-
Molecular Weight 255.34
-
Formula C10H17N5OS
-
Color White to off-white
-
SMILES
[N-]=[N+]=NCCCCC[C@H]1[C@]2([H])[C@@](CS1)([H])NC(N2)=O
-
Synonyms
DecarboxyBiotin-N3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (391.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9163 mL | 19.5817 mL | 39.1635 mL | 97.9087 mL |
| 5 mM | 0.7833 mL | 3.9163 mL | 7.8327 mL | 19.5817 mL | |
| 10 mM | 0.3916 mL | 1.9582 mL | 3.9163 mL | 9.7909 mL | |
| 15 mM | 0.2611 mL | 1.3054 mL | 2.6109 mL | 6.5272 mL | |
| 20 mM | 0.1958 mL | 0.9791 mL | 1.9582 mL | 4.8954 mL | |
| 25 mM | 0.1567 mL | 0.7833 mL | 1.5665 mL | 3.9163 mL | |
| 30 mM | 0.1305 mL | 0.6527 mL | 1.3054 mL | 3.2636 mL | |
| 40 mM | 0.0979 mL | 0.4895 mL | 0.9791 mL | 2.4477 mL | |
| 50 mM | 0.0783 mL | 0.3916 mL | 0.7833 mL | 1.9582 mL | |
| 60 mM | 0.0653 mL | 0.3264 mL | 0.6527 mL | 1.6318 mL | |
| 80 mM | 0.0490 mL | 0.2448 mL | 0.4895 mL | 1.2239 mL | |
| 100 mM | 0.0392 mL | 0.1958 mL | 0.3916 mL | 0.9791 mL |