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  4. Biotin-C5-Azide

Biotin-C5-Azide  (Synonyms: DecarboxyBiotin-N3)

Cat. No.: HY-151667 Purity: 98.92%
COA
SDS
Handling Instructions Technical Support

Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates. Biotin-C5-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

Biotin-C5-Azide

Biotin-C5-Azide Chemical Structure

CAS No. : 1260586-88-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
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Based on 1 publication(s) in Google Scholar

Biotin-C5-Azide Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent and can be used to prepare biotinylated conjugates[1]. Biotin-C5-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

In Vitro

Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension—Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Biotin-C5-Azide Related Antibodies
Molecular Weight

255.34

Formula

C10H17N5OS
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[N-]=[N+]=NCCCCC[C@H]1[C@]2([H])[C@@](CS1)([H])NC(N2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (391.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9163 mL 19.5817 mL 39.1635 mL
5 mM 0.7833 mL 3.9163 mL 7.8327 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.92%

SDS (393 KB)

COA (245 KB) HNMR (265 KB) LCMS (88 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9163 mL 19.5817 mL 39.1635 mL 97.9087 mL
5 mM 0.7833 mL 3.9163 mL 7.8327 mL 19.5817 mL
10 mM 0.3916 mL 1.9582 mL 3.9163 mL 9.7909 mL
15 mM 0.2611 mL 1.3054 mL 2.6109 mL 6.5272 mL
20 mM 0.1958 mL 0.9791 mL 1.9582 mL 4.8954 mL
25 mM 0.1567 mL 0.7833 mL 1.5665 mL 3.9163 mL
30 mM 0.1305 mL 0.6527 mL 1.3054 mL 3.2636 mL
40 mM 0.0979 mL 0.4895 mL 0.9791 mL 2.4477 mL
50 mM 0.0783 mL 0.3916 mL 0.7833 mL 1.9582 mL
60 mM 0.0653 mL 0.3264 mL 0.6527 mL 1.6318 mL
80 mM 0.0490 mL 0.2448 mL 0.4895 mL 1.2239 mL
100 mM 0.0392 mL 0.1958 mL 0.3916 mL 0.9791 mL
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Biotin-C5-Azide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Biotin-C5-Azide1260586-88-6DecarboxyBiotin-N3Fluorescent DyeInhibitorinhibitorinhibit

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