Biotin-DEVD-CHO TFA
Biotin-DEVD-CHO (TFA) is a biotin-conjugated form of the caspase-3 and -7 inhibitor – Ac-DEVD-CHO. Biotin-DEVD-CHO (TFA) can be used for affinity purification of the active caspase-3, -6, -7, and -8. Biotin-DEVD-CHO (TFA) can detect the active caspase-3 in vitro.
For research use only. We do not sell to patients.
- Formula: C30H43F3N6O14S
- Molecular Weight:800.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 800.75
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Formula C30H43F3N6O14S
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Sequence
{Biotin}-Asp-Glu-Val-Asp-CHO
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Sequence Shortening
{Biotin}-DEVD-CHO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nicholson, D. W., et al., (1995). Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature, 376(6535), 37–43. [Content Brief]
[2]. Kumar, S., & Dorstyn, L. (2009). Analysing caspase activation and caspase activity in apoptotic cells. Methods in molecular biology (Clifton, N.J.), 559, 3–17. [Content Brief]
[3]. Suria, H., et al., (1999). Cytoskeletal disruption induces T cell apoptosis by a caspase-3 mediated mechanism. Life sciences, 65(25), 2697–2707. [Content Brief]
[4]. Sohn, D., et al., (2005). Caspase-8 can be activated by interchain proteolysis without receptor-triggered dimerization during drug-induced apoptosis. The Journal of biological chemistry, 280(7), 5267–5273. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Biotin-DEVD-CHO TFA Related Classifications
HY-P5830A Related Classifications
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