Biotin-LC-LC-NHS 

Biotin-LC-LC-NHS is a SMCC cross-linking reagent that can be used to mark antibody and other small molecules, such as Paclitaxel^[1][2].

Biotinylation of antibodies is accomplished by the reaction of Biotin-LC-LC-NHS (1 mg/mL in dimethyl formamide) with the protein in aqueous phase pH 7.4. The molar ratio of biotin to antibody in the labeling reaction was 10:1 (the final concentration of biotin was 70 μM) ^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

567.70

Solid

C₂₆H₄₁N₅O₇S

89889-52-1

O=C(NCCCCCC(NCCCCCC(ON1C(CCC1=O)=O)=O)=O)CCCC[[email protected]@H]2SC[[email protected]]([[email protected]]2([H])N3)([H])NC3=O

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

• [1]. K Dill, et al. Immunoassays Based on Electrochemical Detection Using Microelectrode Arrays. Biosens Bioelectron. 2004 Nov 1;20(4):736-42.  [Content Brief]

  [2]. Lev G Lis, et al. Synthesis and Biological Evaluation of a Biotinylated Paclitaxel With an Extra-Long Chain Spacer Arm. ACS Med Chem Lett . 2012 Sep 13;3(9):745-748.  [Content Brief]