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  3. Iodoacetyl-LC-biotin

Iodoacetyl-LC-biotin 

Cat. No.: HY-138065
Handling Instructions

Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes.

For research use only. We do not sell to patients.

Iodoacetyl-LC-biotin Chemical Structure

Iodoacetyl-LC-biotin Chemical Structure

CAS No. : 93285-75-7

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Description

Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].

In Vitro

Iodoacetyl-LC-biotin (IAB) (50-200 μM; 6-24 h) increases LDH leakage in HEK293 cells in a time- and dose-dependant manner[1].
IAB (50-200 µM; 24 h) causes the release of cytochrome c from the mitochondria to the cytosol in HEK293 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

510.43

Formula

C₁₈H₃₁IN₄O₃S

CAS No.

93285-75-7

SMILES

O=C(NCCCCCCNC(CI)=O)CCCC[[email protected]]1[[email protected]](NC2=O)([H])[[email protected]](N2)([H])CS1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Iodoacetyl-LC-biotinApoptosisbiotinylatedelectrophileprobeInhibitorinhibitorinhibit

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Iodoacetyl-LC-biotin
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