2. Apoptosis
  3. Apoptosis
  4. Iodoacetyl-LC-biotin

Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes.

For research use only. We do not sell to patients.

Iodoacetyl-LC-biotin Chemical Structure

Iodoacetyl-LC-biotin Chemical Structure

CAS No. : 93285-75-7

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Based on 1 publication(s) in Google Scholar

Iodoacetyl-LC-biotin Related Antibodies

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Description

Iodoacetyl-LC-biotin is a biotinylated electrophile probe that can be used to investigate the scope and characteristics of protein covalent binding to subcellular proteomes[1][2].

In Vitro

Iodoacetyl-LC-biotin (IAB) (50-200 μM; 6-24 h) increases LDH leakage in HEK293 cells in a time- and dose-dependant manner[1].
IAB (50-200 µM; 24 h) causes the release of cytochrome c from the mitochondria to the cytosol in HEK293 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Iodoacetyl-LC-biotin Related Antibodies
Molecular Weight

510.43

Formula

C18H31IN4O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCCCCCCNC(CI)=O)CCCC[C@H]1[C@](NC2=O)([H])[C@](N2)([H])CS1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Iodoacetyl-LC-biotin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Iodoacetyl-LC-biotin93285-75-7ApoptosisbiotinylatedelectrophileprobeInhibitorinhibitorinhibit

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