Diazo Biotin-PEG3-alkyne
Based on 1 Customer Validation
Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 98.07%
- CAS No.: 1884349-58-9
- Formula: C39H53N7O9S
- Molecular Weight:795.94
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1884349-58-9
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Appearance Solid
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Molecular Weight 795.94
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Formula C39H53N7O9S
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Color Orange to reddish brown
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SMILES
O=C(NCCOCCOCCOCCNC(C1=CC=C(/N=N/C2=CC(CCNC(CCOCC#C)=O)=CC=C2O)C=C1)=O)CCCC[C@@H]3SC[C@]([C@]3([H])N4)([H])NC4=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (157.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2564 mL | 6.2819 mL | 12.5638 mL | 31.4094 mL |
| 5 mM | 0.2513 mL | 1.2564 mL | 2.5128 mL | 6.2819 mL | |
| 10 mM | 0.1256 mL | 0.6282 mL | 1.2564 mL | 3.1409 mL | |
| 15 mM | 0.0838 mL | 0.4188 mL | 0.8376 mL | 2.0940 mL | |
| 20 mM | 0.0628 mL | 0.3141 mL | 0.6282 mL | 1.5705 mL | |
| 25 mM | 0.0503 mL | 0.2513 mL | 0.5026 mL | 1.2564 mL | |
| 30 mM | 0.0419 mL | 0.2094 mL | 0.4188 mL | 1.0470 mL | |
| 40 mM | 0.0314 mL | 0.1570 mL | 0.3141 mL | 0.7852 mL | |
| 50 mM | 0.0251 mL | 0.1256 mL | 0.2513 mL | 0.6282 mL | |
| 60 mM | 0.0209 mL | 0.1047 mL | 0.2094 mL | 0.5235 mL | |
| 80 mM | 0.0157 mL | 0.0785 mL | 0.1570 mL | 0.3926 mL | |
| 100 mM | 0.0126 mL | 0.0628 mL | 0.1256 mL | 0.3141 mL |
Diazo Biotin-PEG3-alkyne Related Classifications
HY-140925 Related Classifications
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