5-PT TFA
Based on 1 publication(s) in Google Scholar
5-PT (5-Propargyltryptamide) TFA is an alkyne-functionalized derivative of 5-HT (HY-B1473A) and serotonylation substrate that can be taken up by living cells. After conjugation with biotin, 5-PT TFA enables the identification of serotonylated proteins via copper click chemistry and mass spectrometry. 5-PT TFA can label and isolate serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT TFA is applicable to research related to bronchopulmonary dysplasia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3117303-22-4
- 分子式: C15H15F3N2O3
- 分子量:328.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 5-PT TFA
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生物活性
5-PT (100 μM; 24 h) TFA labels 121 unique serotonylated proteins in MLE-12 alveolar epithelial cells, with many of these proteins linked to cellular processes and cell behavior regulation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3117303-22-4
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分子量 328.29
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分子式 C15H15F3N2O3
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SMILES
O=C(C(F)(F)F)O.C#CCOC1=CC2=C(NC=C2CCN)C=C1
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別名
5-Propargyltryptamide TFA
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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iScience
2025 Nov 19;28(12):114120. PMID: 41438086
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)