3117303-22-4
Chemical Structure
5-PT TFA
Synonym(s): 5-Propargyltryptamide TFA
- CAS No.: 3117303-22-4
- Formula:C15H15F3N2O3
- Molecular Weight:328.29
InChIKey: KMVGKGFGNFLVCU-UHFFFAOYSA-N
SMILES: O=C(C(F)(F)F)O.C#CCOC1=CC2=C(NC=C2CCN)C=C1
Biological Activity: 5-PT (5-Propargyltryptamide) TFA is an alkyne-functionalized derivative of 5-HT (HY-B1473A) and serotonylation substrate that can be taken up by living cells. After conjugation with biotin, 5-PT TFA enables the identification of serotonylated proteins via copper click chemistry and mass spectrometry. 5-PT TFA can label and isolate serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT TFA is applicable to research related to bronchopulmonary dysplasia[1].
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5-PT TFA | 5-PT (5-Propargyltryptamide) TFA is an alkyne-functionalized derivative of 5-HT (HY-B1473A) and serotonylation substrate that can be taken up by living cells. After conjugation with biotin, 5-PT TFA enables the identification of serotonylated proteins via copper click chemistry and mass spectrometry. 5-PT TFA can label and isolate serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT TFA is applicable to research related to bronchopulmonary dysplasia. | |||||||||||||||||||||
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Keywords
