Biotin-PEGn-NHS ester
Based on 1 Customer Validation
Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- CAS 番号: 365441-71-0
- 分子式: (C2H4O)nC19H28N4O7S
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 365441-71-0
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性状 Viscous Liquid
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分子式 (C2H4O)nC19H28N4O7S
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Color Colorless to light yellow
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SMILES
O=C1NC2CSC(C2N1)CCCCC(NCCOCCOCCC(ON3C(CCC3=O)=O)=O)=O.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
純度とドキュメンテーション
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データシート (264 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Maldiney T, et al. In vitro targeting of avidin-expressing glioma cells with biotinylated persistent luminescence nanoparticles. Bioconjug Chem. 2012 Mar 21;23(3):472-8. [Content Brief]
[2]. Deng D, et al. Biotin-Avidin System-Based Delivery Enhances the Therapeutic Performance of MSC-Derived Exosomes. ACS Nano. 2023 May 9;17(9):8530-8550. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)