365441-71-0
365441-71-0
Chemical Structure
Biotin-PEGn-NHS ester
- CAS No.: 365441-71-0
- Formula:(C2H4O)nC19H28N4O7S
- Molecular Weight:N/A
SMILES: O=C1NC2CSC(C2N1)CCCCC(NCCOCCOCCC(ON3C(CCC3=O)=O)=O)=O.[n]
Biological Activity: Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Biotin-PEGn-NHS ester | 95.0% | Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA). | ||||||||||||||||||||
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References
- [1]. Maldiney T, et al. In vitro targeting of avidin-expressing glioma cells with biotinylated persistent luminescence nanoparticles. Bioconjug Chem. 2012 Mar 21;23(3):472-8. [Content Brief]
- [2]. Deng D, et al. Biotin-Avidin System-Based Delivery Enhances the Therapeutic Performance of MSC-Derived Exosomes. ACS Nano. 2023 May 9;17(9):8530-8550. [Content Brief]
Keywords
