15-Deoxy-Δ12,14-Prostaglandin J2-biotin
15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin-labled 15-Deoxy-Δ12,14-Prostaglandin J2 (HY-108568). 15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin can be used as a fluorescent probe.
For research use only. We do not sell to patients.
- Formula: C35H54N4O4S
- Molecular Weight:626.89
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Storage:
Solution, -20°C, protect from light, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Liquid
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Molecular Weight 626.89
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Formula C35H54N4O4S
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Color Colorless to light yellow
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SMILES
O=C1C=C[C@@H](/C1=C\C=C\CCCCC)C/C=C\CCCC(NCCCCCNC(CCCC[C@@H]2[C@@]3([C@]([H])(CS2)NC(N3)=O)[H])=O)=O
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Synonyms
15-Deoxy-Δ12,14-PGJ2-biotin
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, protect from light, 2 years
Purity & Documentation
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Data Sheet (266 KB)
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SDS (545 KB)
- English - EN (545 KB)
- Français - FR (545 KB)
- Deutsch - DE (545 KB)
- Norwegian - NO (545 KB)
- Español - ES (545 KB)
- Swedish - SV (545 KB)
- Italian - IT (545 KB)
- Korean - KR (545 KB)
- Portuguese - PT (545 KB)
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Handling Instructions (2659 KB)
References
[1]. Reddy AT, et al. Identification and Molecular Characterization of Peroxisome Proliferator-Activated Receptor δ as a Novel Target for Covalent Modification by 15-Deoxy-Δ12,14-prostaglandin J2. CS Chem Biol. 2018 Dec 21;13(12):3269-3278. [Content Brief]
[2]. Kliewer SA1, et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 1995 Dec 1;83(5):813-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
15-Deoxy-Δ12,14-Prostaglandin J2-biotin Related Classifications
HY-D3313 Related Classifications
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