Biotin-PEG2-OH
Based on 1 publication(s) in Google Scholar
Biotin-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 717119-80-7
- Formula: C14H25N3O4S
- Molecular Weight:331.43
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Biotin-PEG2-OH
MoreAll PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 717119-80-7
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Appearance Solid
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Molecular Weight 331.43
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Formula C14H25N3O4S
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Color White to off-white
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SMILES
O=C(NCCOCCO)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Redox Biol
Overexpression of NUDT16L1 sustains proper function of mitochondria and leads to ferroptosis insensitivity in colorectal cancer. [Abstract]2024 Nov:77:103358. PMID: 39317106
Solvent & Solubility
DMSO : 100 mg/mL (301.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0172 mL | 15.0861 mL | 30.1723 mL | 75.4307 mL |
| 5 mM | 0.6034 mL | 3.0172 mL | 6.0345 mL | 15.0861 mL | |
| 10 mM | 0.3017 mL | 1.5086 mL | 3.0172 mL | 7.5431 mL | |
| 15 mM | 0.2011 mL | 1.0057 mL | 2.0115 mL | 5.0287 mL | |
| 20 mM | 0.1509 mL | 0.7543 mL | 1.5086 mL | 3.7715 mL | |
| 25 mM | 0.1207 mL | 0.6034 mL | 1.2069 mL | 3.0172 mL | |
| 30 mM | 0.1006 mL | 0.5029 mL | 1.0057 mL | 2.5144 mL | |
| 40 mM | 0.0754 mL | 0.3772 mL | 0.7543 mL | 1.8858 mL | |
| 50 mM | 0.0603 mL | 0.3017 mL | 0.6034 mL | 1.5086 mL | |
| 60 mM | 0.0503 mL | 0.2514 mL | 0.5029 mL | 1.2572 mL | |
| 80 mM | 0.0377 mL | 0.1886 mL | 0.3772 mL | 0.9429 mL | |
| 100 mM | 0.0302 mL | 0.1509 mL | 0.3017 mL | 0.7543 mL |
Biotin-PEG2-OH Related Classifications
HY-135911 Related Classifications
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