m7(3'Ma-Biotin)Gppp(2'OMe)ApG ammonium solution (25mM) 

m7(3'Ma-Biotin)Gppp(2'OMe)ApG ammonium is a Biotin-labled cap analogue that can be used for mRNA synthesis. The efficiency of mRNA delivery can be determined by the detection of Biotin by flow cytometry, which can be used to track mRNA in cells and in living animals and to screen delivery lipid ratios.

1385.00 (free base)

C₄₃H₆₀N₁₈O₂₅P₄S.xNH₃

Liquid

Colorless to light yellow

O=C1C([N+](C)=CN2[C@H]3[C@H](O)[C@H](CNC(CCCC[C@@H]4SC[C@]([C@]4([H])N5)([H])NC5=O)=O)[C@@H](COP(OP(OP(OC[C@H]6O[C@@H](N(C=N7)C8=C7C(N)=NC=N8)[C@H](OC)[C@@H]6OP(OC[C@H]9O[C@@H](N(C=N%10)C%11=C%10C(NC(N)=N%11)=O)[C@H](O)[C@@H]9O)([O-])=O)(O)=O)(O)=O)(O)=O)O3)=C2N=C(N)N1.N.[x]

Room temperature in continental US; may vary elsewhere.

Solution, -20°C, 2 years